Development of anti-human mesothelin chimeric antigen receptor (CAR) messenger RNA (mRNA) transfected peripheral blood mononuclear cells (CARMA) for the treatment of mesothelin-expressing cancers

被引:0
|
作者
Hung, Chien-Fu
Xu, Xuequn
Li, Linhong
Ma, Ying
Jin, Qiu
Viley, Angelia
Allen, Cornell
Natarajan, Pachai
Shivakumar, Rama
Peshwa, Madhusudan V.
Emens, Leisha A.
机构
关键词
D O I
10.1158/1538-7445.AM2017-3748
中图分类号
R73 [肿瘤学];
学科分类号
100214 ;
摘要
3748
引用
收藏
页数:2
相关论文
共 6 条
  • [1] Development of Anti-Human Mesothelin-Targeted Chimeric Antigen Receptor Messenger RNA-transfected Peripheral Blood Lymphocytes for Ovarian Cancer Therapy
    Hung, Chien-Fu
    Xu, Xuequn
    Li, Linhong
    Ma, Ying
    Jin, Qiu
    Viley, Angelia
    Allen, Cornell
    Natarajan, Pachai
    Shivakumar, Rama
    Peshwa, Madhusudan V.
    Emens, Leisha A.
    HUMAN GENE THERAPY, 2018, 29 (05) : 614 - 625
  • [2] Development of a Regulated, Optimized Mesothelin Chimeric Antigen Receptor (CAR) for the Treatment of Mesothelin Positive Cancers
    Yokoyama, Jason
    Wang, Allan
    Steele, Maria
    Crowl, John
    Davenport, Thaddeus
    Hammer, Jared
    Obenza, Willimark
    Montoya, Vanessa
    Kirkpatrick, Robin
    Baker, Laura
    Tan, Tina
    Bringgold, Emily
    Shirley, Kristie
    Deshmukh, Maanasee
    Hammerson, Bradley
    Sample, Paul
    Weitzner, Brian
    Yuan, Shujun
    Foster, Aaron
    Lajoie, Marc
    Boyken, Scott
    Moffett, Howell
    Amin, Rupesh
    BLOOD, 2023, 142
  • [3] Construction and Functional Characterization of a Fully Human Anti-mesothelin Chimeric Antigen Receptor (CAR) Expressing T Cell
    Jafarzadeh, Leila
    Masoumi, Elham
    Alishah, Khadijeh
    Mirzaei, Hamid Reza
    Jamali, Arezoo
    Fallah-Mehrjardi, Keyvan
    Rostamian, Hosein
    Khakpoor-Koosheh, Mohammad
    Meshkani, Reza
    Noorbakhsh, Farshid
    Hadjati, Jamshid
    IRANIAN JOURNAL OF ALLERGY ASTHMA AND IMMUNOLOGY, 2020, 19 (03) : 264 - 275
  • [4] Human peripheral blood mononuclear cells transfected with messenger RNA stimulate antigen-specific cytotoxic T-lymphocytes in vitro
    Teufel, R
    Carralot, JP
    Scheel, B
    Probst, J
    Walter, S
    Jung, G
    Hoerr, I
    Rammensee, HG
    Pascolo, S
    CELLULAR AND MOLECULAR LIFE SCIENCES, 2005, 62 (15) : 1755 - 1762
  • [5] CHIMERIC ANTIGEN RECEPTOR (CAR) MESSENGER RNA (MRNA) LOADED FRESHLY ISOLATED PERIPHERAL BLOOD LYMPHOCYTES AS A POINT-OF-CARE TARGETED TUMOR IMMUNOTHERAPY
    Li, L.
    Allen, C.
    Natarajan, P.
    Peshwa, M. V.
    CYTOTHERAPY, 2014, 16 (04) : S37 - S37
  • [6] Bypassing the Constraint for Chimeric Antigen Receptor (CAR) Development in T-Cells Expressing the Targeted Antigen: Improvement of Anti-CS1 CAR Activity in Allogenic TCRa/CS1 Double Knockout T-Cells for the Treatment of Multiple Myeloma (MM)
    Galetto, Roman
    Chion-Sotinel, Isabelle
    Gouble, Agnes
    Smith, Julianne
    BLOOD, 2015, 126 (23)