Microfabrication of biomaterials by the sub-ps laser-induced forward transfer process

被引：65
|
作者：
Karaiskou, A
Zergioti, I
Fotakis, C
Kapsetaki, M
Kafetzopoulos, D
机构：
[1] FORTH, IESL, Iraklion 71110, Crete, Greece
[2] Inst Mol Biol & Biotechnol, Iraklion 71110, Crete, Greece
来源：
APPLIED SURFACE SCIENCE | 2003年 / 208卷
关键词：
laser microprinting; DNA microarrays; laser-induced forward transfer;
D O I：
10.1016/S0169-4332(02)01396-X
中图分类号：
O64 [物理化学（理论化学）、化学物理学];
学科分类号：
070304 ; 081704 ;
摘要：
The precise fabrication of micro-dimensioned patterns of biomaterials by the laser microprinting technique using a sub-ps UV laser is described. An ultrashort UV laser has been used to transfer the biomaterial, with low angular divergence, and deposit it onto the substrate with minimum spread and high spatial resolution. The laser-transferred features of 100mum x 100 mum size have been studied by means of scanning electron microscopy and scanning laser confocal fluorescence microscopy. The analysis of DNA and protein microarrays provides an excellent tool to expand our knowledge of genome functions. (C) 2003 Elsevier Science B.V. All rights reserved.
引用
收藏
页码：245 / 249
页数：5
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