Natural Killer cells in embryo-implantation

被引：0

作者：

Harsa, Radu ^{[1
]}

Nedelea, Irena ^{[2
]}

Surcel, Mihai ^{[1
]}

Stamatian, Florin ^{[1
]}

Micu, Romeo ^{[1
]}

机构：

[1] Univ Med & Pharm Iuliu Hatieganu Cluj Napoca, Gynecol Clin 1, Dept Human Assisted Reprod, Cluj Napoca, Romania

[2] Univ Med & Pharm Iuliu Hatieganu Cluj Napoca, Dept Allergy & Immunol, Cluj Napoca, Romania

来源：

ROMANIAN BIOTECHNOLOGICAL LETTERS | 2019年 / 24卷 / 05期

关键词：

Uterine natural killer; embryo implantation; infertility; RECURRENT SPONTANEOUS-ABORTION; IN-VITRO FERTILIZATION; METRIAL GLAND-CELLS; FETAL HLA-C; PERIPHERAL-BLOOD; NK-CELLS; EARLY-PREGNANCY; IVF TREATMENT; MATERNAL KIR; WOMEN;

D O I：

10.25083/rbl/24.5/789.797

中图分类号：

Q81 [生物工程学（生物技术）]; Q93 [微生物学];

学科分类号：

071005 ; 0836 ; 090102 ; 100705 ;

摘要：

Infertility is a global public health problem. Despite progresses in assisted reproductive technologies, failure of treatment exists and poses a difficult challenge to both clinicians and infertile couples. A myriad of factors causes failure of embryo implantation. However, in a significant percentage of the cases, the aetiology remains a topic of study and interpretation. Current data suggest that both peripheral blood and uterine natural killer cells might play a role in successful implantation and subsequent conception. In this paper, we aim to discuss the importance of NK cells in embryo-implantation and the reproductive outcome, as illustrated by current literature.

引用

页码：789 / 797

页数：9

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