Contraceptive effects of Phyllanthus amarus extracts in the male mouse (Mus musculus)

被引：0
|
作者：
Rao, MV [1 ]
Shah, KD
Rajani, M
机构：
[1] Gujarat Univ, Div Reprod Physiol & Enocrine Toxicol, Dept Zool, Ahmedabad 380009, Gujarat, India
[2] Sarkhej Gandhinagar Highway, PERD Ctr, Ahmedabad, Gujarat, India
来源：
PHYTOTHERAPY RESEARCH | 1997年 / 11卷 / 08期
关键词：
Phyllanthus plant extract; functional sterility; organ metabolism; mouse sperm;
D O I：
10.1002/(SICI)1099-1573(199712)11:8<594::AID-PTR157>3.0.CO;2-4
中图分类号：
R914 [药物化学];
学科分类号：
100701 ;
摘要：
Feeding an alcohol extract of Phyllanthus at a dose of 500 mg/kg for 45 days induced gradual inhibition of fertility potential in male albino mice with a decline in epididymal sperm profiles, However, no effects were observed in gravimetric analysis, Similarly no adverse changes were found in the blood biochemical profile and cell counts, Upon withdrawal of feeding the extract to mice, the observed antifertility effects were reversed gradually, indicating induction of functional sterility. (C) 1997 John Wiley & Sons, Ltd.
引用
收藏
页码：594 / 596
页数：3
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