Occult SARS-CoV-2 infection; a possible hypothesis for viral relapse

被引:5
|
作者
Elberry, Mostafa H. [1 ]
Ahmed, Hussien [2 ,3 ]
机构
[1] Cairo Univ, Natl Canc Inst, Canc Biol Dept, Virol & Immunol Unit, Cairo, Egypt
[2] Arizona State Univ, Edson Coll, Clin Res Management Program, Tempe, AZ 85281 USA
[3] Zagazig Univ, Fac Med, Zagazig, Sharkia, Egypt
关键词
RESPIRATORY SYNDROME CORONAVIRUS; SARS-CORONAVIRUS; ACE2; PATHOGENESIS; REPLICATION; CELLS; RNA;
D O I
10.1016/j.mehy.2020.109980
中图分类号
R-3 [医学研究方法]; R3 [基础医学];
学科分类号
1001 ;
摘要
Coronavirus disease 2019 (COVID-19) has emerged as a global public health emergency, which is characterized by high infection rate and fatal course. Recent data reported that the test for Severe Acute Respiratory Syndrome Coronavirus-2 (SARS-CoV-2) RNA might become positive again after one or two consecutively negative tests. Many researchers are currently evaluating the clinical characteristics of the SARS-CoV-2 reactivation. In this letter, we proposed a possible mechanism of SARS-CoV-2 reactivation or relapse after negative nasopharyngeal swabs PCR.
引用
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页数:3
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