Continuous production of inorganic magnetic nanocomposites for biomedical applications by laser pyrolysis

被引:28
|
作者
Veintemillas-Verdaguer, Sabino
Leconte, Yann
Costo, Rocio
Bomati-Miguel, Oscar
Bouchet-Fabre, Brigitte
Morales, M. Puerto
Bonville, Pierre
Perez-Rial, Sandra
Rodriguez, Ignacio
Herlin-Boime, Nathalie
机构
[1] CSIC, Inst Ciencia Mat Madrid, E-28049 Madrid, Spain
[2] CEA, CNRS, URA 2453, SPAM LFP, F-91191 Gif Sur Yvette, France
[3] CEA, CE Saclay, Serv Phys Etat Condense, F-91191 Gif Sur Yvette, France
[4] UCM, Unidad RMN, Madrid 28040, Spain
关键词
composites material; laser pyrolysis; magnetization curve; magnetic nanoparticle; colloid; contrast enhancement; magnetic resonance imaging; encapsulation;
D O I
10.1016/j.jmmm.2006.10.1200
中图分类号
T [工业技术];
学科分类号
08 ;
摘要
Magnetic composites of Fe-based nanoparticles encapsulated in carbon/silica (C/SiO2@Fe) or carbon (C@Fe) matrices were prepared by laser-induced pyrolysis of aerosols. The powders were dispersed in aqueous solutions at pH 7 resulting in biocompatible colloidal dispersions with a high resistance to biodegradation. Structural and magnetic properties and the suitability of aqueous dispersions as contrast agent for MRI were analyzed. The results of these characterizations and the NMR relaxivity data are very encouraging for application of laser pyrolysis products in the field of living tissues. (C) 2006 Elsevier B.V. All rights reserved.
引用
收藏
页码:120 / 124
页数:5
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