Effect of injectable equine collagen type I on metabolic activity and apoptosis of gingival fibroblasts

被引：3
|
作者：
Klewin-Steinbock, Sylwia [1 ]
Nowak-Terpilowska, Agnieszka [2 ]
Adamski, Zygmunt [3 ]
Grocholewicz, Katarzyna [4 ]
Wyganowska-Swiatkowska, Marzena [1 ]
机构：
[1] Poznan Univ Med Sci, Dept Dent Surg & Periodontol, 70 Bukowska St, PL-60820 Poznan, Poland
[2] Poznan Univ Life Sci, Dept Biochem & Biotechnol, Poznan, Poland
[3] Poznan Univ Med Sci, Dept Dermatol, Poznan, Poland
[4] Pomeranian Med Univ, Dept Interdisciplinary Dent, Szczecin, Poland
来源：
POSTEPY DERMATOLOGII I ALERGOLOGII | 2021年 / 38卷 / 03期
关键词：
gingival fibroblasts; equine collagen; cytotoxicity; apoptosis; HETEROGENEITY; ATELOCOLLAGEN; MATRIX;
D O I：
10.5114/ada.2020.94256
中图分类号：
R392 [医学免疫学];
学科分类号：
100102 ;
摘要：
Collagen as a biomaterial is widely used for tissue regeneration due to various advantages including its biodegradation, biocompatibility, and low allergenicity. Along with aesthetic medicine development, collagen is also used in the injectable form as a tissue biostimulator. The area of our study was collagen's impact on fibroblast activity and apoptosis. The research showed that atelocollagen decreases metabolic activity of fibroblasts, but also showed an increasing number of living cells after 48 h and 72 h incubation under the influence of collagen.
引用
收藏
页码：440 / 445
页数：6
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