Gene-edited healthy donor CAR T cells show superior anti-tumour activity compared to CAR T cells derived from patients with lymphoma in an in vivo model of high-grade lymphoma

被引：16
|
作者：
Graham, Charlotte Elizabeth [1 ,2 ]
Jozwik, Agnieszka [1 ]
Quartey-Papafio, Ruby [1 ]
Ioannou, Nikolaos [1 ]
Metelo, Ana M. [1 ]
Scala, Carlo [1 ]
Dickson, Glenda [1 ]
Stewart, Orla [2 ]
Almena-Carrasco, Maria [3 ]
Peranzoni, Elisa [3 ]
Ramsay, Alan G. [1 ]
Patten, Piers E. M. [1 ,2 ]
Pertel, Thomas [4 ]
Farzaneh, Farzin [1 ]
Dupouy, Sandra [3 ]
Pepper, Andrea [5 ]
Benjamin, Reuben [1 ,2 ]
机构：
[1] Kings Coll London, Fac Life Sci & Med, Sch Canc & Pharmaceut Sci, London, England
[2] Kings Coll Hosp NHS Fdn Trust, London, England
[3] Inst Rech Int Servier, Paris, France
[4] Allogene Therapeut, San Francisco, CA USA
[5] Univ Sussex, Brighton & Sussex Med Sch, Brighton, E Sussex, England
来源：
LEUKEMIA | 2021年 / 35卷 / 12期
基金：
英国生物技术与生命科学研究理事会; 英国工程与自然科学研究理事会;
关键词：
B-CELL;
D O I：
10.1038/s41375-021-01324-z
中图分类号：
R73 [肿瘤学];
学科分类号：
100214 ;
摘要：
[No abstract available]
引用
收藏
页码：3581 / 3584
页数：4
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