Visible-Light-Induced C (sp3)-H Functionalization of Tosylhydrazones: Synthesis of Polysubstituted Pyrroles under Metal-Free Conditions

被引：19
|
作者：
Reddy, N. Naresh Kumar [1 ]
Rawat, Deepa [1 ]
Adimurthy, Subbarayappa [1 ]
机构：
[1] Cent Salt & Marine Chem Res Inst, CSIR, Acad Sci & Innovat Res, GB Marg, Bhavnagar 364002, Gujarat, India
来源：
JOURNAL OF ORGANIC CHEMISTRY | 2018年 / 83卷 / 16期
关键词：
EFFICIENT SYNTHESIS; N-TOSYLHYDRAZONES; METHYL KETONES; IODINE; CYCLOADDITION; AMINATION;
D O I：
10.1021/acs.joc.8b00878
中图分类号：
O62 [有机化学];
学科分类号：
070303 ; 081704 ;
摘要：
Iodine catalyzed C (sp(3))-H functionalization of tosylhydrazones with beta-enamino esters under visible light irradiation for the synthesis of trisubstituted pyrroles has been described. The present method is also applicable to a alpha-substituted tosylhydrazones to yield the tetra-substituted pyrroles.
引用
收藏
页码：9412 / 9421
页数：10
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