Clinical and pharmacokinetic study with a lipidic prodrug of mitomycin-c entrapped in liposomes in metastatic colorectal cancer patients

被引：0
|
作者：
Gabizon, Alberto A. [1 ]
Tahover, Esther [1 ]
Perets, Ruth [2 ]
Golan, Talia [3 ]
Geva, Ravit [4 ]
Amitay, Yasmine [5 ]
Shmeeda, Hilary [1 ]
Ohana, Patricia [1 ]
机构：
[1] Shaare Zedek Med Ctr, Jerusalem, Israel
[2] Rambam Hlth Care Campus, Haifa, Israel
[3] Sheba Med Ctr, Ramat Gan, Israel
[4] Tel Aviv Sourasky Med Ctr, Tel Aviv, Israel
[5] Lipomedix Pharmaceut, Jerusalem, Israel
来源：
CANCER RESEARCH | 2019年 / 79卷 / 13期
关键词：
D O I：
10.1158/1538-7445.AM2019-CT054
中图分类号：
R73 [肿瘤学];
学科分类号：
100214 ;
摘要：
CT054
引用
收藏
页数：2
相关论文
共 50 条
  • [1] Pharmacokinetics of mitomycin-c lipidic prodrug entrapped in liposomes and clinical correlations in metastatic colorectal cancer patients
    Gabizon, Alberto A.
    Tahover, Esther
    Golan, Talia
    Geva, Ravit
    Perets, Ruth
    Amitay, Yasmine
    Shmeeda, Hilary
    Ohana, Patricia
    INVESTIGATIONAL NEW DRUGS, 2020, 38 (05) : 1411 - 1420
  • [2] Pharmacokinetics of mitomycin-c lipidic prodrug entrapped in liposomes and clinical correlations in metastatic colorectal cancer patients
    Alberto A. Gabizon
    Esther Tahover
    Talia Golan
    Ravit Geva
    Ruth Perets
    Yasmine Amitay
    Hilary Shmeeda
    Patricia Ohana
    Investigational New Drugs, 2020, 38 : 1411 - 1420
  • [3] Mitomycin-c (mtc) as salvage therapy for patients with metastatic colorectal cancer (mCRC)
    Jelena, Spasic
    Nemanja, Stanic
    Fedja, Djordjevic
    Marija, Ristic
    Vladimir, Nikolic
    Davorin, Radosavljevic
    ANNALS OF ONCOLOGY, 2017, 28
  • [4] CLINICAL STUDY OF MITOMYCIN-C (NSC-26980) IN COLORECTAL CANCER
    ANSFIELD, FJ
    CANCER CHEMOTHERAPY REPORTS PART 1, 1969, 53 (05): : 287 - &
  • [5] Mitomycin-C and Capecitabine (MIXE) as Salvage Treatment in Patients with Refractory Metastatic Colorectal Cancer: A Retrospective Study
    Saif, Muhammad Wasif
    Kaley, Kristin
    Brennan, Marianne
    Garcon, Marie Carmel
    Rodriguez, Gladys
    ANTICANCER RESEARCH, 2013, 33 (06) : 2743 - 2746
  • [6] Development of Promitil®, a lipidic prodrug of mitomycin c in PEGylated liposomes: From bench to bedside
    Gabizon, Alberto
    Shmeeda, Hilary
    Tahover, Esther
    Kornev, Gleb
    Patil, Yogita
    Amitay, Yasmine
    Ohana, Patricia
    Sapir, Eli
    Zalipsky, Samuel
    ADVANCED DRUG DELIVERY REVIEWS, 2020, 154 (154-155) : 13 - 26
  • [7] MITOMYCIN-C PHARMACOKINETICS IN PATIENTS WITH RECURRENT OR METASTATIC COLORECTAL-CARCINOMA
    ERLICHMAN, C
    RAUTH, AM
    BATTISTELLA, R
    FINE, S
    CANADIAN JOURNAL OF PHYSIOLOGY AND PHARMACOLOGY, 1987, 65 (03) : 407 - 411
  • [8] Capecitabine and mitomycin-C in the therapy of pretreated patients with metastatic colorectal cancer: single center retrospective study with 36 patients
    Vrdoljak, E.
    Omrcen, T.
    Boban, M.
    Hrepic, D.
    JOURNAL OF BUON, 2008, 13 (04): : 513 - 518
  • [9] ABSORPTION CHARACTERISTICS OF THE LIPOPHILIC PRODRUG OF MITOMYCIN-C FROM INJECTED LIPOSOMES OR AN EMULSION
    SASAKI, H
    KAKUTANI, T
    HASHIDA, M
    SEZAKI, H
    JOURNAL OF PHARMACY AND PHARMACOLOGY, 1985, 37 (07) : 461 - 465
  • [10] UFT/leucovorin combined with mitomycin-C in metastatic colorectal Ca
    Jakobsen, A
    ONCOLOGY-NEW YORK, 2000, 14 (10): : 32 - 34
12345