Glucose lowering effect of the protracted GLP-1 derivative, NN2211, in the betacell reduced minipig

被引：0
|
作者：
Ribel, U [1 ]
Hvidt, M [1 ]
Larsen, MO [1 ]
Rolin, B [1 ]
Wilken, M [1 ]
Knudsen, LB [1 ]
机构：
[1] Novo Nordisk AS, DK-2880 Bagsvaerd, Denmark
来源：
DIABETOLOGIA | 2000年 / 43卷
关键词：
D O I：
暂无
中图分类号：
R5 [内科学];
学科分类号：
1002 ; 100201 ;
摘要：
560
引用
收藏
页码：A145 / A145
页数：1
相关论文
共 50 条
  • [1] An immunoassay for the GLP-1 derivative NN2211
    Wilken, M
    Larsen, FS
    Juul, AG
    Jensen, LB
    Ribel, U
    DIABETOLOGIA, 2000, 43 : A148 - A148
  • [2] Pharmacodynamics of NN2211, a novel long acting GLP-1 derivative
    Agerso, H
    Vicini, P
    EUROPEAN JOURNAL OF PHARMACEUTICAL SCIENCES, 2003, 19 (2-3) : 141 - 150
  • [3] The GLP-1 derivative NN2211 normalizes food intake and lowers body weight in a hyperphagic minipig model
    Raun, K
    Von Voss, P
    Ankersen, T
    Bollen, P
    Knudsen, LB
    DIABETES, 2003, 52 : A325 - A325
  • [4] Effect of the long-acting GLP-1 derivative NN2211 in 60% pancreatectomized rats
    Romer, J
    Pedersen, KE
    Jorgensen, B
    Rothe, P
    Bentsen, E
    Damgaard, N
    Knudsen, LB
    Wassermann, K
    Ribel, U
    DIABETES, 2001, 50 : A312 - A312
  • [5] Effect of the long-acting GLP-1 derivative NN2211 in 60% pancreatectomized rats
    Romer, J
    Bentsen, E
    Damgaard, J
    Jorgensen, B
    Pedersen, KE
    Rothe, P
    Knudsen, LB
    Wassermann, K
    Ribel, U
    DIABETOLOGIA, 2001, 44 : A197 - A197
  • [6] NN2211, a GLP-1 derivative, has a long lasting blood glucose lowering effect in db/db mice: A comparison with exendin-4
    Larsen, MO
    Rolin, B
    Wilken, M
    Carr, RD
    Knudsen, LB
    DIABETES, 2001, 50 : A312 - A312
  • [7] NN2211, a protracted GLP-1 derivative, ameliorates glycaemia and reduces triglyceride levels in pre-diabetic ZDF rats
    Rolin, B
    Gotfredsen, C
    Sturis, J
    Wilken, M
    Nygaard, H
    Carr, RD
    Knudsen, LB
    DIABETES, 2001, 50 : A312 - A312
  • [8] Pharmacokinetic profile of the long-acting GLP-1 derivative NN2211 in healthy male subjects
    Jakobsen, G
    Agerso, H
    Elbroend, B
    Jensen, LB
    DIABETES, 2001, 50 : A118 - A118
  • [9] NN2211, a long-acting derivative of GLP-1, lowers blood glucose in ob/ob and db/db mice
    Larsen, MO
    Rolin, B
    Wilken, M
    Carr, RD
    Knudsen, LB
    DIABETES, 2000, 49 : A1 - A1
  • [10] The GLP-1 derivative NN2211 restores β-cell sensitivity to glucose in type 2 diabetic patients after a single dose
    Chang, AM
    Jakobsen, G
    Sturis, J
    Smith, MJ
    Bloem, CJ
    An, B
    Galecki, A
    Halter, JB
    DIABETES, 2003, 52 (07) : 1786 - 1791
12345