Melanin-concentrating hormone and sleep

被引:36
|
作者
Pacheco Ferreira, Jozelia Gomes [1 ,3 ]
Bittencourt, Jackson Cioni [1 ,2 ]
Adamantidis, Antoine [3 ,4 ]
机构
[1] Univ Sao Paulo, Dept Anat, Inst Biomed Sci, Sao Paulo, Brazil
[2] Univ Sao Paulo, Neurosci & Behav Ctr, Inst Psychol, Sao Paulo, Brazil
[3] Univ Bern, Dept Neurol, Inselspital Univ Hosp, Bern, Switzerland
[4] Univ Bern, Dept Clin Res, Inselspital Univ Hosp, Bern, Switzerland
基金
巴西圣保罗研究基金会; 欧洲研究理事会; 瑞士国家科学基金会;
关键词
EYE-MOVEMENT SLEEP; MESSENGER-RIBONUCLEIC-ACID; CENTRAL-NERVOUS-SYSTEM; PARADOXICAL REM SLEEP; TO-WAKE TRANSITIONS; SLOW-WAVE SLEEP; MCH NEURONS; BRAIN-STEM; OREXIN/HYPOCRETIN NEURONS; OPTOGENETIC ACTIVATION;
D O I
10.1016/j.conb.2017.04.008
中图分类号
Q189 [神经科学];
学科分类号
071006 ;
摘要
The melanin-concentrating hormone (MCH) is an essential neuromodulator involved with homeostatic regulation and motivated behaviors. The majority of MCH neurons are localized within the zona incerta, lateral hypothalamic and incerto-hypothalamic areas but others regions, as the olfactory turbecle, the laterodorsal tegmental nucleus, the paramediam pontine reticular formation and the medial preoptic area, can also express the peptide depending on the gender and metabolic state of the animal. If the MCH on these novel sites of expression are also related with the control of wake-sleep cycle will be discuss in this review.
引用
收藏
页码:152 / 158
页数:7
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