The following paper discusses the importance of establishing communication channels between academia, the media, and the public with respect to the development of biotechnology within Sub-Saharan Africa. Citing evidence from interviews with specialists in genetic science, science journalism and public education, the paper reflects on the problems associated with developing multidisciplinary discussion within academic circles, communication between natural scientists and the media, and ultimately the exchange of knowledge between science and society. The major findings from these interviews is that while there is a shared objective and realisation that science communication is important for the development. of the region, this objective is hampered by a lack of understanding and trust between scientists and the scientific media. A pattern of mistrust has developed whereby local experts tend to talk to journalists from outside the region rather than from Africa. As a result, there is little opportunity for scientists and the media to communicate the relevance of genetics and biotechnology for the region's development. By way of conclusion, the paper discusses the positive indicators for science communication across the region, based on demand for knowledge, empowerment of scientists and the public, and the urgency of the regional food crisis. Copyright (c) 2010 John Wiley & Sons, Ltd.