(p)ppGpp target ribosome assembly

被引：3
|
作者：
Nunes-Alves, Claudio
机构：
来源：
NATURE REVIEWS MICROBIOLOGY | 2016年 / 14卷 / 05期
关键词：
D O I：
10.1038/nrmicro.2016.44
中图分类号：
Q93 [微生物学];
学科分类号：
071005 ; 100705 ;
摘要：
This study shows that, as part of the stringent response inStaphylococcus aureus, (p)ppGpp target GTPases, impairing their ability to mediate ribosome assembly, which affects bacterial growth and promotes tolerance to antimicrobials.
引用
收藏
页码：266 / 266
页数：1
相关论文
共 50 条
  • [1] (p)ppGpp target ribosome assembly
    Cláudio Nunes-Alves
    Nature Reviews Microbiology, 2016, 14 : 266 - 266
  • [2] Ribosome Assembly as Antimicrobial Target
    Nikolay, Rainer
    Schmidt, Sabine
    Schloemer, Renate
    Deuerling, Elke
    Nierhaus, Knud H.
    ANTIBIOTICS-BASEL, 2016, 5 (02):
  • [3] Ribosome Assembly in Trypanosomatids: A Novel Therapeutic Target
    Kamina, Anyango D.
    Williams, Noreen
    TRENDS IN PARASITOLOGY, 2017, 33 (04) : 256 - 257
  • [4] Inhibition of Bacterial Ribosome Assembly: a Suitable Drug Target?
    Maguire, Bruce A.
    MICROBIOLOGY AND MOLECULAR BIOLOGY REVIEWS, 2009, 73 (01) : 22 - 35
  • [5] Expression of a small (p)ppGpp synthetase, YwaC, in the (p)ppGpp0 mutant of Bacillus subtilis triggers YvyD-dependent dimerization of ribosome
    Tagami, Kazumi
    Nanamiya, Hideaki
    Kazo, Yuka
    Maehashi, Marie
    Suzuki, Shota
    Namba, Eri
    Hoshiya, Masahiro
    Hanai, Ryo
    Tozawa, Yuzuru
    Morimoto, Takuya
    Ogasawara, Naotake
    Kageyama, Yasushi
    Ara, Katsutoshi
    Ozaki, Katsuya
    Yoshida, Masaki
    Kuroiwa, Haruko
    Kuroiwa, Tsuneyoshi
    Ohashi, Yoshiaki
    Kawamura, Fujio
    MICROBIOLOGYOPEN, 2012, 1 (02): : 115 - 134
  • [6] ppGpp negatively impacts ribosome assembly affecting growth and antimicrobial tolerance in Gram-positive bacteria
    Corrigan, Rebecca M.
    Bellows, Lauren E.
    Wood, Alison
    Gruendling, Angelika
    PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 2016, 113 (12) : E1710 - E1719
  • [7] How the initiating ribosome copes with ppGpp to translate mRNAs
    Vinogradova, Daria S.
    Zegarra, Victor
    Maksimova, Elena
    Alberto Nakamoto, Jose
    Kasatsky, Pavel
    Paleskava, Alena
    Konevega, Andrey L.
    Milon, Pohl
    PLOS BIOLOGY, 2020, 18 (01)
  • [8] ppGpp ribosome dimerization model for bacterial persister formation and resuscitation
    Song, Sooyeon
    Wood, Thomas K.
    BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS, 2020, 523 (02) : 281 - 286
  • [9] (p)ppGpp: Still Magical?
    Potrykus, Katarzyna
    Cashel, Michael
    ANNUAL REVIEW OF MICROBIOLOGY, 2008, 62 : 35 - 51
  • [10] Expression of ribosome modulation factor (RMF) in Escherichia coli requires ppGpp
    Izutsu, K
    Wada, A
    Wada, C
    GENES TO CELLS, 2001, 6 (08) : 665 - 676
12345