Polymer-supported mukaiyama reagent: A useful coupling reagent for the synthesis of esters and amides

被引:53
|
作者
Crosignani, S [1 ]
Gonzalez, J [1 ]
Swinnen, D [1 ]
机构
[1] Serono Pharmaceut Res Inst, CH-1228 Geneva, Switzerland
关键词
D O I
10.1021/ol0480372
中图分类号
O62 [有机化学];
学科分类号
070303 ; 081704 ;
摘要
[GRAPHICS] Polymer-supported N-alkyl-2-chloro pyridinium triflate was synthesized in one step from Wang resin. This reagent proved to be a very effective coupling reagent for the synthesis of esters or amides from carboxylic acids and alcohols or amines (primary and secondary).
引用
收藏
页码:4579 / 4582
页数:4
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