Enzymatic esterifications of functionalized phenols for the synthesis of lipophilic antioxidants

被引：100

作者：

Buisman, GJH ^{[1
]}

van Helteren, CTW ^{[1
]}

Kramer, GFH ^{[1
]}

Veldsink, JW ^{[1
]}

Derksen, JTP ^{[1
]}

Cuperus, FP ^{[1
]}

机构：

[1] DLO, Agrotechnol Res Inst, ATO, NL-6700 AA Wageningen, Netherlands

来源：

BIOTECHNOLOGY LETTERS | 1998年 / 20卷 / 02期

关键词：

D O I：

10.1023/A:1005368222340

中图分类号：

Q81 [生物工程学（生物技术）]; Q93 [微生物学];

学科分类号：

071005 ; 0836 ; 090102 ; 100705 ;

摘要：

Of seven lipases used to esterify functionalized phenols and fatty acids to synthesize lipophilic antioxidants, that from Candida antarctica lipase B (CAL-B) had the highest catalytic activity. Esterification yields of benzoic acid derivatives catalyzed by CAL-B are below 2% after 7 days. In contrast, relatively high yields were obstained for the esterification of (poly) phenols bearing primary hydroxy groups and aliphatic acids (85% yield within 15 hours). Crude products were purified and used as lipophilic antioxidants in sunflower oil.

引用

页码：131 / 136

页数：6

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