Hypoxia increases heat shock protein 90 binding (Hsp90) to endothelial nitric oxide synthase (eNOS) via a P13-Akt pathway in porcine coronary artery endothelium (PCAEC)

被引：0

作者：

Chen, JX ^{[1
]}

Meyrick, B ^{[1
]}

机构：

[1] Vanderbilt Univ, Med Ctr, Nashville, TN 37232 USA

来源：

FASEB JOURNAL | 2003年 / 17卷 / 05期

关键词：

D O I：

暂无

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

引用

页码：A805 / A805

页数：1

共 34 条

[1] Hypoxia increases Hsp90 binding to eNOS via PI3K-Akt in porcine coronary artery endothelium
Chen, JX
Meyrick, B
LABORATORY INVESTIGATION, 2004, 84 (02) : 182 - 190
[2] Inhibition of heat shock protein 90 (hsp90) uncouples endothelial nitric oxide synthase (eNOS) activity independent of oxidative stress
Ou, JS
Ou, ZJ
Ackerman, AW
Oldham, KT
Pritchard, KA
FREE RADICAL BIOLOGY AND MEDICINE, 2002, 33 : S323 - S323
[3] Functional interdependence and spatial colocalization of endothelial nitric oxide synthase (eNOS) and heat-shock protein 90 (HSP90) in cerebral arteries
Khurana, GV
Feterik, K
Springett, MJ
Eguchi, D
Shah, V
Toft, DO
Katusic, ZS
CIRCULATION, 2000, 102 (18) : 321 - 321
[4] Inhibition of heat shock protein 90 (hsp90) in proliferating endothelial cells uncouples endothelial nitric oxide synthase activity
Ou, J
Ou, Z
Ackerman, AW
Oldham, KT
Pritchard, KA
FREE RADICAL BIOLOGY AND MEDICINE, 2003, 34 (02) : 269 - 276
[5] Role of endothelial nitric oxide synthase (eNOS) phosphorylation and heat shock protein 90 (Hsp90)-eNOS association in the vasodilator response to physiologic stimuli pulmonary circulation
Konduri, GG
Eis, AL
Bakhulashvili, IV
PEDIATRIC RESEARCH, 2004, 55 (04) : 436A - 436A
[6] Post-translational modification of endothelial nitric oxide synthase (eNOS) by heat shock protein 90 (Hsp90): Effects on newborn pulmonary vascular tone
Aschner, JL
Basehore, MJ
Lecras, TD
CIRCULATION, 2001, 104 (17) : 206 - 206
[7] Decreased association of heat shock protein 90 (hsp90) impairs endothelial nitric oxide synthase (eNOS) in fetal lambs with persistent pulmonary hypertension of newborn (PPHN)
Konduri, GG
Ou, JS
Yang, S
Pritchard, KA
PEDIATRIC RESEARCH, 2003, 53 (04) : 352A - 352A
[8] Heatshock protein 90 (Hsp90) regulates endothelial nitric oxide synthase (eNOS) generation of nitric oxide (NO) and superoxide anion (O2•).
Pritchard, KA
Gross, E
Ackerman, AW
Stepp, DW
Fontana, J
Sessa, WC
FASEB JOURNAL, 2001, 15 (05): : A781 - A781
[9] Endothelial nitric oxide synthase regulation II: HSP90 and protein kinase Akt synergistically activate eNOS by forming a ternary complex
Takahashi, S
Mendelsohn, ME
CIRCULATION, 2002, 106 (19) : 211 - 212
[10] Synergistic activation of endothelial nitric-oxide synthase (eNOS) by HSP90 and Akt - Calcium-independent eNOS activation involves formation of an HSP90-Akt-CaM-BOUND eNOS complex
Takahashi, S
Mendelsohn, ME
JOURNAL OF BIOLOGICAL CHEMISTRY, 2003, 278 (33) : 30821 - 30827

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