Electrospun starch nanofibers: Recent advances, challenges, and strategies for potential pharmaceutical applications

被引：158
|
作者：
Liu, Guodong [1 ,2 ,3 ]
Gu, Zhengbiao [1 ,2 ,3 ]
Hong, Yan [1 ,2 ,3 ]
Cheng, Li [1 ,2 ,3 ]
Li, Caiming [1 ,2 ,3 ]
机构：
[1] Jiangnan Univ, State Key Lab Food Sci & Technol, 1800 Lihu Ave, Wuxi 214122, Jiangsu, Peoples R China
[2] Jiangnan Univ, Sch Food Sci & Technol, 1800 Lihu Ave, Wuxi 214122, Jiangsu, Peoples R China
[3] Jiangnan Univ, Collaborat Innovat Ctr Food Safety & Qual Control, 1800 Lihu Ave, Wuxi 214122, Jiangsu, Peoples R China
来源：
JOURNAL OF CONTROLLED RELEASE | 2017年 / 252卷
基金：
中国国家自然科学基金;
关键词：
Starch; Electrospinning; Nanofibers; Drug delivery; Tissue engineering; Wound dressing; TISSUE-ENGINEERING SCAFFOLDS; DRUG-DELIVERY SYSTEMS; HIGH-AMYLOSE STARCH; COMPOSITE NANOFIBERS; POLY(VINYL ALCOHOL); CROSS-LINKING; RHEOLOGICAL PROPERTIES; SURFACE MODIFICATION; DEBRANCHED STARCHES; FORMING NANOFIBRES;
D O I：
10.1016/j.jconrel.2017.03.016
中图分类号：
O6 [化学];
学科分类号：
0703 ;
摘要：
Electrospun starch nanofibers have high porosity, extremely high specific surface area, and biocompatible, biodegradable, and bioabsorbable properties. As a result, starch nanofibers have great potential in pharmaceutical applications, including drug delivery, wound dressing, and tissue engineering. Here, we summarize and review the recent developments in the synthesis of electrospun starch fibers from common starch, modified starch, and hybrids with other polymers. Moreover, the challenges and strategies for the fabrication and application of starch fibers in pharmaceutical applications are presented. (C) 2017 Elsevier B. V. All rights reserved.
引用
收藏
页码：95 / 107
页数：13
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