Effect of Chain Length of Alcohol on the Lipase-Catalyzed Esterification of Propionic Acid in Supercritical Carbon Dioxide

被引：22
|
作者：
Varma, Mahesh N. [1 ]
Madras, Giridhar [1 ]
机构：
[1] Indian Inst Sci, Dept Chem Engn, Bangalore 560012, Karnataka, India
来源：
APPLIED BIOCHEMISTRY AND BIOTECHNOLOGY | 2010年 / 160卷 / 08期
关键词：
Supercritical carbon dioxide; Novozym; 435; Esterification; Primary alcohol; Secondary alcohol; Ping-Pong Bi-Bi mechanism; ENZYMATIC-SYNTHESIS; IMMOBILIZED LIPASE; METHYL ACETOACETATE; ORGANIC-SOLVENT; ESTER SYNTHESIS; KINETICS; TRANSESTERIFICATION; BUTYRATE; ISOBUTYRATE; ACETATE;
D O I：
10.1007/s12010-009-8696-7
中图分类号：
Q5 [生物化学]; Q7 [分子生物学];
学科分类号：
071010 ; 081704 ;
摘要：
The esterification of propionic acid was investigated using three different alcohols, namely, isopropyl alcohol, isobutyl alcohol, and isoamyl alcohol. The variation of conversion with time for the synthesis of isoamyl propionate was investigated in the presence of five enzymes. Novozym 435 showed the highest activity, and this was used as the enzyme for investigating the various parameters that influence the esterification reaction. The Ping-Pong Bi-Bi model with inhibition by both acid and alcohol was used to model the experimental data and determine the kinetics of the esterification reaction.
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页码：2342 / 2354
页数：13
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