Expanding the Donor Pool Donation After Cardiac Death

被引：16
|
作者：
Elgharably, Haytham [1 ]
Shafii, Alexis E. [2 ]
Mason, David P. [2 ]
机构：
[1] Cleveland Clin, Dept Thorac & Cardiovasc Surg, Cleveland, OH 44195 USA
[2] Baylor Univ, Med Ctr, Dept Thorac Surg & Lung Transplantat, Dallas, TX 75246 USA
来源：
THORACIC SURGERY CLINICS | 2015年 / 25卷 / 01期
关键词：
Lung transplantation; Donation after cardiac death; Ex vivo lung perfusion; Outcomes; CANINE LUNG TRANSPLANTATION; HEART-BEATING DONORS; EX-VIVO EVALUATION; LONG-TERM PRESERVATION; POSTMORTEM HEPARINIZATION; PULMONARY-EMBOLISM; ORGAN PROCUREMENT; RETROGRADE FLUSH; EARLY OUTCOMES; GRAFT FUNCTION;
D O I：
10.1016/j.thorsurg.2014.09.011
中图分类号：
R56 [呼吸系及胸部疾病];
学科分类号：
摘要：
Lung transplantation (LTx) is the definitive treatment of patients with end-stage lung disease. Availability of donor lungs remains the primary limitation and leads to substantial wait-list mortality. Efforts to expand the donor pool have included a resurgence of interest in the use of donation after cardiac death (DOD) lungs. Unique in its physiology, lung viability seems more tolerant to the variable durations of ischemia that occur in DCD donors. Initial experience with DOD LTx is promising and, in combination with ex vivo lung perfusion systems, seems a valuable opportunity to expand the lung donor pool.
引用
收藏
页码：35 / +
页数：13
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