Structure, synthesis, and biological properties of kalkitoxin, a novel neurotoxin from the marine cyanobacterium Lyngbya majuscula

被引:124
|
作者
Wu, M
Okino, T
Nogle, LM
Marquez, BL
Williamson, RT
Sitachitta, N
Berman, FW
Murray, TF
McGough, K
Jacobs, R
Colsen, K
Asano, T
Yokokawa, F
Shioiri, T [1 ]
Gerwick, WH
机构
[1] Oregon State Univ, Coll Pharm, Corvallis, OR 97331 USA
[2] Univ Georgia, Coll Vet Med, Dept Physiol & Pharmacol, Athens, GA 30601 USA
[3] Univ Calif Santa Barbara, Dept Pharmacol, Santa Barbara, CA 93106 USA
[4] Bruker Instruments Inc, Billerica, MA 01821 USA
[5] Nagoya City Univ, Fac Pharmaceut Sci, Mizuho Ku, Nagoya, Aichi 4678603, Japan
关键词
D O I
10.1021/ja005526y
中图分类号
O6 [化学];
学科分类号
0703 ;
摘要
引用
收藏
页码:12041 / 12042
页数:2
相关论文
共 50 条
  • [1] Total synthesis and biological evaluation of (+)-kalkitoxin, a cytotoxic metabolite of the cyanobacterium Lyngbya majuscula
    White, JD
    Xu, Q
    Chang, CS
    Valeriote, FA
    ORGANIC & BIOMOLECULAR CHEMISTRY, 2004, 2 (14) : 2092 - 2102
  • [2] Total structure and biological properties of laxaphycins A and B, cyclic lipopeptides from the marine cyanobacterium Lyngbya majuscula
    Bonnard, I
    Rolland, M
    Francisco, C
    Banaigs, B
    LETTERS IN PEPTIDE SCIENCE, 1997, 4 (4-6): : 289 - 292
  • [3] Total structure and biological properties of laxaphycins A and B, cyclic lipopeptides from the marine cyanobacterium Lyngbya majuscula
    Isabelle Bonnard
    Marc Rolland
    Christian Francisco
    Bernard Banaigs
    Letters in Peptide Science, 1997, 4 : 289 - 292
  • [4] Isolation, structure determination, and biological activity of lyngbyabellin A from the marine cyanobacterium Lyngbya majuscula
    Luesch, H
    Yoshida, WY
    Moore, RE
    Paul, VJ
    Mooberry, SL
    JOURNAL OF NATURAL PRODUCTS, 2000, 63 (05): : 611 - 615
  • [5] Total structure determination of apratoxin A, a potent novel cytotoxin from the marine cyanobacterium Lyngbya majuscula
    Luesch, H
    Yoshida, WY
    Moore, RE
    Paul, VJ
    Corbett, TH
    JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 2001, 123 (23) : 5418 - 5423
  • [6] Besarhanamides A and B from the marine cyanobacterium Lyngbya majuscula
    Tan, Lik Tong
    Chang, Ying Yan
    Ashootosh, Tripathi
    PHYTOCHEMISTRY, 2008, 69 (10) : 2067 - 2069
  • [7] Natural antifoulants from the marine cyanobacterium Lyngbya majuscula
    Tan, Lik Tong
    Goh, Beverly Pi Lee
    Tripathi, Ashootosh
    Lim, Mui Gek
    Dickinson, Gary H.
    Lee, Serina Siew Chen
    Teo, Serena Lay Ming
    BIOFOULING, 2010, 26 (06) : 685 - 695
  • [8] Apramides A-G, novel lipopeptides from the marine cyanobacterium Lyngbya majuscula
    Luesch, H
    Yoshida, WY
    Moore, RE
    Paul, VJ
    JOURNAL OF NATURAL PRODUCTS, 2000, 63 (08): : 1106 - 1112
  • [9] Three new malyngamides from the marine cyanobacterium Lyngbya majuscula
    Wu, M
    Milligan, KE
    Gerwick, WH
    TETRAHEDRON, 1997, 53 (47) : 15983 - 15990
  • [10] Total synthesis of antillatoxin, an ichthyotoxic cyclic lipopeptide from marine cyanobacterium Lyngbya majuscula
    Yokokawa, F
    Shioiri, T
    JOURNAL OF SYNTHETIC ORGANIC CHEMISTRY JAPAN, 2000, 58 (07) : 634 - 641