Background Despite the evidence base for computer-assisted cognitive behavioural therapy (CBT) in the general population, it has not yet been adapted for use with adults who have an intellectual disability. Alms To evaluate the utility of a CBT computer game for adults who have an intellectual disability. Method A 2 x 3 (group x time) randomised controlled trial design was used. Fifty-two adults with mild to moderate intellectual disability and anxiety or depression were randomly allocated to two groups: computerised CBT (cCBT) or psychiatric treatment as usual (TAU), and assessed at pre-treatment, post-treatment and 3-month follow-up. Forty-nine participants were included in the final analysis. Results A significant group x time interaction was observed on the primary outcome measure of anxiety (Glasgow Anxiety Scale for people with an Intellectual Disability), favouring cCBT over O'Reilly TAU, but not on the primary outcome measure of depression (Glasgow Depression Scale for people with a Learning Disability). A medium effect size for anxiety symptoms was observed at post-treatment and a large effect size was observed after follow-up. Reliability of Change Indices indicated that the intervention produced clinically significant change in the cCBT group in comparison with TAU. Conclusions As the first application of cCBT for adults with intellectual disability, this intervention appears to be a useful treatment option to reduce anxiety symptoms in this population.
机构:
UCL Mental Hlth Sci Unit, London W1W 7EJ, EnglandUCL Mental Hlth Sci Unit, London W1W 7EJ, England
Hassiotis, Angela
Serfaty, Marc
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UCL Mental Hlth Sci Unit, London W1W 7EJ, England
Priory Hosp North London, The Bourne, London N14 6RA, EnglandUCL Mental Hlth Sci Unit, London W1W 7EJ, England
Serfaty, Marc
Azam, Kiran
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Goodmayes Hosp, Res & Dev, Goodmayes IG3 8XJ, Essex, EnglandUCL Mental Hlth Sci Unit, London W1W 7EJ, England
Azam, Kiran
Strydom, Andre
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UCL Mental Hlth Sci Unit, London W1W 7EJ, EnglandUCL Mental Hlth Sci Unit, London W1W 7EJ, England
Strydom, Andre
Blizard, Robert
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机构:
UCL, Mol Psychiat Lab, Res Dept Mental Hlth Sci, London WC1E 6JJ, EnglandUCL Mental Hlth Sci Unit, London W1W 7EJ, England
Blizard, Robert
Romeo, Renee
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机构:
Kings Coll London, Inst Psychiat, CEMPH, David Goldberg Ctr, London SE5 8AF, EnglandUCL Mental Hlth Sci Unit, London W1W 7EJ, England
Romeo, Renee
Martin, Sue
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Islington Learning Disabil Partnership, London N5 1NS, EnglandUCL Mental Hlth Sci Unit, London W1W 7EJ, England
Martin, Sue
King, Michael
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h-index: 0
机构:
UCL Mental Hlth Sci Unit, London W1W 7EJ, EnglandUCL Mental Hlth Sci Unit, London W1W 7EJ, England
机构:
Newcastle Upon Tyne Hosp NHS Fdn Trust, RVI Hosp, Chest Clin, Newcastle Upon Tyne, Tyne & Wear, England
Newcastle Univ, Med Sch, Inst Cellular Med, Newcastle Upon Tyne, Tyne & Wear, EnglandNewcastle Upon Tyne Hosp NHS Fdn Trust, RVI Hosp, Chest Clin, Newcastle Upon Tyne, Tyne & Wear, England
Heslop-Marshall, Karen
Baker, Christine
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h-index: 0
机构:
Newcastle Upon Tyne Hosp NHS Fdn Trust, RVI Hosp, Dept Clin Hlth Psychol, Newcastle Upon Tyne, Tyne & Wear, EnglandNewcastle Upon Tyne Hosp NHS Fdn Trust, RVI Hosp, Chest Clin, Newcastle Upon Tyne, Tyne & Wear, England
Baker, Christine
Carrick-Sen, Debbie
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h-index: 0
机构:
Univ Birmingham, Sch Med & Dent Sci, Nursing Dept, Birmingham, W Midlands, England
Heart England NHS Trust, Birmingham, W Midlands, EnglandNewcastle Upon Tyne Hosp NHS Fdn Trust, RVI Hosp, Chest Clin, Newcastle Upon Tyne, Tyne & Wear, England
Carrick-Sen, Debbie
Newton, Julia
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h-index: 0
机构:
Newcastle Univ, Med Sch, Inst Cellular Med, Newcastle Upon Tyne, Tyne & Wear, EnglandNewcastle Upon Tyne Hosp NHS Fdn Trust, RVI Hosp, Chest Clin, Newcastle Upon Tyne, Tyne & Wear, England
Newton, Julia
Echevarria, Carlos
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h-index: 0
机构:
Newcastle Upon Tyne Hosp NHS Fdn Trust, RVI Hosp, Chest Clin, Newcastle Upon Tyne, Tyne & Wear, England
Newcastle Univ, Med Sch, Inst Cellular Med, Newcastle Upon Tyne, Tyne & Wear, EnglandNewcastle Upon Tyne Hosp NHS Fdn Trust, RVI Hosp, Chest Clin, Newcastle Upon Tyne, Tyne & Wear, England
Echevarria, Carlos
Stenton, Chris
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h-index: 0
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Newcastle Upon Tyne Hosp NHS Fdn Trust, RVI Hosp, Chest Clin, Newcastle Upon Tyne, Tyne & Wear, EnglandNewcastle Upon Tyne Hosp NHS Fdn Trust, RVI Hosp, Chest Clin, Newcastle Upon Tyne, Tyne & Wear, England
Stenton, Chris
Jambon, Michelle
论文数: 0引用数: 0
h-index: 0
机构:
Newcastle Upon Tyne Hosp NHS Fdn Trust, RVI Hosp, Commun Chest Team, Newcastle Upon Tyne, Tyne & Wear, EnglandNewcastle Upon Tyne Hosp NHS Fdn Trust, RVI Hosp, Chest Clin, Newcastle Upon Tyne, Tyne & Wear, England
Jambon, Michelle
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Gray, Joanne
Pearce, Kim
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Newcastle Univ, Med Sch, Inst Cellular Med, Newcastle Upon Tyne, Tyne & Wear, EnglandNewcastle Upon Tyne Hosp NHS Fdn Trust, RVI Hosp, Chest Clin, Newcastle Upon Tyne, Tyne & Wear, England
Pearce, Kim
Burns, Graham
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h-index: 0
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Newcastle Upon Tyne Hosp NHS Fdn Trust, RVI Hosp, Chest Clin, Newcastle Upon Tyne, Tyne & Wear, EnglandNewcastle Upon Tyne Hosp NHS Fdn Trust, RVI Hosp, Chest Clin, Newcastle Upon Tyne, Tyne & Wear, England
Burns, Graham
De Soyza, Anthony
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h-index: 0
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Newcastle Univ, Med Sch, Inst Cellular Med, Newcastle Upon Tyne, Tyne & Wear, EnglandNewcastle Upon Tyne Hosp NHS Fdn Trust, RVI Hosp, Chest Clin, Newcastle Upon Tyne, Tyne & Wear, England
机构:
Univ New S Wales, Ctr Gen Practice Integrat Studies, Sch Publ Hlth & Community Med, Sydney, NSW 2052, AustraliaUniv New S Wales, Ctr Gen Practice Integrat Studies, Sch Publ Hlth & Community Med, Sydney, NSW 2052, Australia
Proudfoot, J
Ryden, C
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h-index: 0
机构:Univ New S Wales, Ctr Gen Practice Integrat Studies, Sch Publ Hlth & Community Med, Sydney, NSW 2052, Australia
Ryden, C
Everitt, B
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h-index: 0
机构:Univ New S Wales, Ctr Gen Practice Integrat Studies, Sch Publ Hlth & Community Med, Sydney, NSW 2052, Australia
Everitt, B
Shapiro, DA
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h-index: 0
机构:Univ New S Wales, Ctr Gen Practice Integrat Studies, Sch Publ Hlth & Community Med, Sydney, NSW 2052, Australia
Shapiro, DA
Goldberg, D
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机构:Univ New S Wales, Ctr Gen Practice Integrat Studies, Sch Publ Hlth & Community Med, Sydney, NSW 2052, Australia
Goldberg, D
Mann, A
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机构:Univ New S Wales, Ctr Gen Practice Integrat Studies, Sch Publ Hlth & Community Med, Sydney, NSW 2052, Australia
Mann, A
Tylee, A
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h-index: 0
机构:Univ New S Wales, Ctr Gen Practice Integrat Studies, Sch Publ Hlth & Community Med, Sydney, NSW 2052, Australia
Tylee, A
Marks, I
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h-index: 0
机构:Univ New S Wales, Ctr Gen Practice Integrat Studies, Sch Publ Hlth & Community Med, Sydney, NSW 2052, Australia
Marks, I
Gray, JA
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机构:Univ New S Wales, Ctr Gen Practice Integrat Studies, Sch Publ Hlth & Community Med, Sydney, NSW 2052, Australia
机构:
London South Bank Univ, Sch Law & Social Sci, Ctr Social Justice & Global Responsibil, London, EnglandKings Coll London, Dept Psychol, London, England
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Univ York, Dept Hlth Sci, York YO10 5DD, N Yorkshire, EnglandUniv York, Dept Hlth Sci, York YO10 5DD, N Yorkshire, England
Littlewood, Elizabeth
Duarte, Ana
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h-index: 0
机构:
Univ York, Ctr Hlth Econ, York YO10 5DD, N Yorkshire, EnglandUniv York, Dept Hlth Sci, York YO10 5DD, N Yorkshire, England
Duarte, Ana
Hewitt, Catherine
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h-index: 0
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Univ York, Dept Hlth Sci, York Trials Unit, York YO10 5DD, N Yorkshire, EnglandUniv York, Dept Hlth Sci, York YO10 5DD, N Yorkshire, England
Hewitt, Catherine
Knowles, Sarah
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Univ Manchester, Inst Populat Hlth, Ctr Primary Care, Manchester, Lancs, England
Univ Manchester, Manchester Acad Hlth Sci Ctr, Sch Primary Care Res, NIHR, Manchester, Lancs, England
Univ Manchester, Natl Primary Care Res & Dev Ctr, Manchester, Lancs, EnglandUniv York, Dept Hlth Sci, York YO10 5DD, N Yorkshire, England
Knowles, Sarah
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Palmer, Stephen
Walker, Simon
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Univ York, Ctr Hlth Econ, York YO10 5DD, N Yorkshire, EnglandUniv York, Dept Hlth Sci, York YO10 5DD, N Yorkshire, England
Walker, Simon
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Andersen, Phil
Araya, Ricardo
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h-index: 0
机构:
Univ Bristol, Acad Unit Psychiat, Bristol, Avon, England
London Sch Hyg & Trop Med, Dept Populat Hlth, London WC1, EnglandUniv York, Dept Hlth Sci, York YO10 5DD, N Yorkshire, England
Araya, Ricardo
Barkham, Michael
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h-index: 0
机构:
Univ Sheffield, Ctr Psychol Serv Res, Sheffield, S Yorkshire, EnglandUniv York, Dept Hlth Sci, York YO10 5DD, N Yorkshire, England
Barkham, Michael
Bower, Peter
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h-index: 0
机构:
Univ Manchester, Manchester Acad Hlth Sci Ctr, Sch Primary Care Res, NIHR, Manchester, Lancs, England
Univ Manchester, Natl Primary Care Res & Dev Ctr, Manchester, Lancs, EnglandUniv York, Dept Hlth Sci, York YO10 5DD, N Yorkshire, England
Bower, Peter
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Brabyn, Sally
Brierley, Gwen
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h-index: 0
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Univ York, Dept Hlth Sci, York YO10 5DD, N Yorkshire, England
Univ Cambridge, Sch Clin Med, Epidemiol Unit, MRC, Cambridge, EnglandUniv York, Dept Hlth Sci, York YO10 5DD, N Yorkshire, England
Brierley, Gwen
Cooper, Cindy
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h-index: 0
机构:
Univ Sheffield, Sch Hlth & Related Res, Clin Trials Res Unit, Sheffield, S Yorkshire, EnglandUniv York, Dept Hlth Sci, York YO10 5DD, N Yorkshire, England
Cooper, Cindy
Gask, Linda
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h-index: 0
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Univ Manchester, Manchester Acad Hlth Sci Ctr, Sch Primary Care Res, NIHR, Manchester, Lancs, England
Univ Manchester, Natl Primary Care Res & Dev Ctr, Manchester, Lancs, EnglandUniv York, Dept Hlth Sci, York YO10 5DD, N Yorkshire, England
Gask, Linda
Kessler, David
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h-index: 0
机构:
Univ Bristol, Acad Unit Primary Hlth Care, Bristol, Avon, EnglandUniv York, Dept Hlth Sci, York YO10 5DD, N Yorkshire, England
Kessler, David
Lester, Helen
论文数: 0引用数: 0
h-index: 0
机构:
Univ Manchester, Manchester Acad Hlth Sci Ctr, Sch Primary Care Res, NIHR, Manchester, Lancs, England
Univ Manchester, Natl Primary Care Res & Dev Ctr, Manchester, Lancs, England
Univ Birmingham, Primary Care Clin Sci, Birmingham, W Midlands, EnglandUniv York, Dept Hlth Sci, York YO10 5DD, N Yorkshire, England
Lester, Helen
Lovell, Karina
论文数: 0引用数: 0
h-index: 0
机构:
Univ Manchester, Sch Nursing Midwifery & Social Work, Manchester, Lancs, EnglandUniv York, Dept Hlth Sci, York YO10 5DD, N Yorkshire, England
Lovell, Karina
Muhammad, Usman
论文数: 0引用数: 0
h-index: 0
机构:
Univ York, Dept Hlth Sci, York Trials Unit, York YO10 5DD, N Yorkshire, EnglandUniv York, Dept Hlth Sci, York YO10 5DD, N Yorkshire, England
Muhammad, Usman
Parry, Glenys
论文数: 0引用数: 0
h-index: 0
机构:
Univ Sheffield, Sch Hlth & Related Res, Clin Trials Res Unit, Sheffield, S Yorkshire, EnglandUniv York, Dept Hlth Sci, York YO10 5DD, N Yorkshire, England
Parry, Glenys
Richards, David A.
论文数: 0引用数: 0
h-index: 0
机构:
Univ York, Dept Hlth Sci, York YO10 5DD, N Yorkshire, England
Univ Exeter, Sch Med, Exeter, Devon, EnglandUniv York, Dept Hlth Sci, York YO10 5DD, N Yorkshire, England
Richards, David A.
Richardson, Rachel
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h-index: 0
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Univ York, Dept Hlth Sci, York YO10 5DD, N Yorkshire, EnglandUniv York, Dept Hlth Sci, York YO10 5DD, N Yorkshire, England
Richardson, Rachel
Tallon, Debbie
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h-index: 0
机构:
Univ Bristol, Sch Social & Community Med, Bristol, Avon, EnglandUniv York, Dept Hlth Sci, York YO10 5DD, N Yorkshire, England
Tallon, Debbie
Tharmanathan, Puvan
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h-index: 0
机构:
Univ York, Dept Hlth Sci, York Trials Unit, York YO10 5DD, N Yorkshire, EnglandUniv York, Dept Hlth Sci, York YO10 5DD, N Yorkshire, England
Tharmanathan, Puvan
White, David
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h-index: 0
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Univ Sheffield, Sch Hlth & Related Res, Clin Trials Res Unit, Sheffield, S Yorkshire, EnglandUniv York, Dept Hlth Sci, York YO10 5DD, N Yorkshire, England
White, David
Gilbody, Simon
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h-index: 0
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Univ York, Dept Hlth Sci, York YO10 5DD, N Yorkshire, EnglandUniv York, Dept Hlth Sci, York YO10 5DD, N Yorkshire, England