Flow injection determination of lomefloxacin based on photochemically sensitized chemiluminescence

被引：6
|
作者：
Sun, CY [1 ]
Lian, N [1 ]
Zhao, HC [1 ]
Yi, L [1 ]
Jin, LP [1 ]
机构：
[1] Beijing Normal Univ, Dept Chem, Beijing 100875, Peoples R China
来源：
MICROCHIMICA ACTA | 2004年 / 148卷 / 1-2期
关键词：
photochemical; chemiluminescence; lomefloxacin; terbium(III);
D O I：
10.1007/s00604-004-0253-z
中图分类号：
O65 [分析化学];
学科分类号：
070302 ; 081704 ;
摘要：
A photochemical chemiluminescence (CL) method for the determination of lomefloxacin (LFX) is proposed. LFX undergoes a photochemical reaction when irradiated with ultraviolet light, and a complex is formed when the photoproduct reacts with terbium(III), which can greatly enhance the CL of the Ce4+ -Na2SO3 system. Under optimum experimental conditions, the linear range is between 9.0 x 10(-10) and 1.0 X 10(-5) M, and the detection limit is 2.2 x 10(-10) M. The relative standard deviation for the determination of 5.0 x 10(-8) M LFX was 3.0% (n = 11). The method has been successfully applied to the determination of LFX in dosage form, serum samples and urine samples. The recoveries were 97.9-102.3% for serum and urine samples. The possible mechanism is presented.
引用
收藏
页码：65 / 70
页数：6
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