CRLX101, an investigational camptothecin-containing nanoparticle-drug conjugate, reverses the HIF-1α-mediated increase in cancer stem cells caused by bevacizumab in a preclinical model of triple-negative breast cancer

被引:1
|
作者
Conley, Sarah J. [1 ]
Baker, Trenton L. [1 ]
Burnet, Joseph P. [1 ]
Thiesen, Rebecca L. [1 ]
Lazarus, Douglas [2 ]
Peters, Christian G. [2 ]
Clouthier, Shawn G. [1 ]
Eliasol, Scott [2 ]
Wicha, Max S. [1 ]
机构
[1] Univ Michigan, Ctr Comprehens Canc, Ann Arbor, MI 48109 USA
[2] Cerulean Pharma Inc, Cambridge, MA USA
关键词
D O I
10.1158/1538-7445.AM2015-1384
中图分类号
R73 [肿瘤学];
学科分类号
100214 ;
摘要
1384
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收藏
页数:1
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