Dose per unit cumulated activity (S-values) for e- and beta emitting radionuclides in cancer cell models calculated by Monte Carlo simulation

被引：7

作者：

Rojas-Calderon, E. L. ^{[1
]}

Torres-Garcia, E. ^{[2
]}

Avila, O. ^{[1
]}

机构：

[1] Inst Nacl Invest Nucl, Ocoyoacac, Estado De Mexic, Mexico

[2] Univ Autonoma Estado Mexico, Toluca 50180, Estado De Mexic, Mexico

来源：

APPLIED RADIATION AND ISOTOPES | 2014年 / 90卷

关键词：

Dose; Molecular radiotherapy; S-values; Monte Carlo; Cancer cells; Radionuclides; PROSTATE-CANCER; THERAPY; NANOPARTICLE;

D O I：

10.1016/j.apradiso.2014.04.012

中图分类号：

O61 [无机化学];

学科分类号：

070301 ; 081704 ;

摘要：

Cell dosimetry is relevant regarding new efforts in specific molecular radiotherapy using Auger, CE and beta emitters. Absorbed dose in cells can be obtained by means of the dose per unit cumulated activity (S-values), together with the activity distribution. In this work, Monte Carlo simulation codes PENELOPE and MCNPX were used to obtain cellular S-values for point and extended sources of electrons and beta emitting radionuclides in the nucleus of breast (MDA-MB231, MCF7) and prostate (PC3) cancer cell models. (C) 2014 Elsevier Ltd. All rights reserved.

引用

页码：229 / 233

页数：5

共 3 条

[1] Monte Carlo-based evaluation of S-values in mouse models for positron-emitting radionuclides
Xie, Tianwu
Zaidi, Habib
PHYSICS IN MEDICINE AND BIOLOGY, 2013, 58 (01): : 169 - 182
[2] Monte Carlo calculated single-cell S-values using a stochastic atomic relaxation model for accurate nuclear data of Auger electron-emitting radionuclides
Falzone, N.
Lee, B. Q.
Fernandez-Varea, J. M.
Stuchbery, A. E.
Kibedi, T.
Vallis, K. A.
EUROPEAN JOURNAL OF NUCLEAR MEDICINE AND MOLECULAR IMAGING, 2016, 43 : S228 - S228
[3] Monte Carlo calculations of the cellular S-values for α-particle-emitting radionuclides incorporated into the nuclei of cancer cells of the MDA-MB231, MCF7 and PC3 lines
Rojas-Calderon, E. L.
Avila, O.
Ferro-Flores, G.
APPLIED RADIATION AND ISOTOPES, 2018, 135 : 1 - 6

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