HIV and renal disease: a contemporary review

被引：18

作者：

Gameiro, Joana ^{[1
]}

Jorge, Sofia ^{[1
]}

Lopes, Jose A. ^{[1
]}

机构：

[1] Ctr Hosp Lisboa Norte, Dept Med, Div Nephrol & Renal Transplantat, EPE Ave Prof Egas Moniz, P-1649035 Lisbon, Portugal

来源：

INTERNATIONAL JOURNAL OF STD & AIDS | 2018年 / 29卷 / 07期

关键词：

HIV; renal disease; ACQUIRED-IMMUNODEFICIENCY-SYNDROME; COMPLEX KIDNEY-DISEASE; INFECTED PATIENTS; RISK-FACTORS; TENOFOVIR ALAFENAMIDE; NEPHROPATHY; ASSOCIATION; PROTEINURIA; MANAGEMENT; OUTCOMES;

D O I：

10.1177/0956462417750710

中图分类号：

R392 [医学免疫学]; Q939.91 [免疫学];

学科分类号：

100102 ;

摘要：

The presence of human immunodeficiency virus (HIV)-related kidney disease is an important cause of mortality and morbidity. HIV infection induces renal injury by direct cytotoxicity or immune complex-mediated glomerulonephritis in patients with genetic susceptibility factors. In the last decades, with the development and diffusion of combination antiretroviral therapy, which has prolonged patient survival, there has been a shift in the spectrum of renal diseases in HIV-infected patients, with the decrease of glomerular diseases and increase in the role of nephrotoxicity and co-morbidities. This review provides a contemporary and critical review on the main renal syndromes occurring in HIV-infected patients.

引用

页码：714 / 719

页数：6

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