The powerful symbiosis between synthetic and medicinal chemistry

被引：15
|
作者：
Schiesser, Stefan [1 ]
Cox, Rhona J. [2 ]
Czechtizky, Werngard [1 ]
机构：
[1] AstraZeneca, Dept Med Chem Res & Early Dev, Resp & Immunol R&I, BioPharmaceut R&D, Pepparedsleden 1, S-43183 Molndal, Sweden
[2] AstraZeneca, Dept Med Chem Res & Early Dev, Cardiovasc Renal & Metab, BioPharmaceut R&D, Pepparedsleden 1, S-43183 Molndal, Sweden
来源：
FUTURE MEDICINAL CHEMISTRY | 2021年 / 13卷 / 11期
关键词：
BCP; bioisostere; bridged bicycle; intellectual property; medicinal chemistry; phosphine oxide; physicochemical properties; sulfoximine; synthesis; trifluoromethyl; TRIFLUOROMETHYL AMINES;
D O I：
10.4155/fmc-2021-0062
中图分类号：
R914 [药物化学];
学科分类号：
100701 ;
摘要：
[No abstract available]
引用
收藏
页码：941 / 944
页数：4
相关论文
共 50 条
  • [1] Fluorine a powerful tool in medicinal chemistry
    Fried, J
    ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY, 1996, 211 : 116 - MEDI
  • [2] Boron in Medicinal Chemistry: Powerful, but Neglected
    Maeder, Patrick
    CHIMIA, 2019, 73 (7-8) : 637 - 638
  • [3] MEDICINAL CHEMISTRY AND SYNTHETIC DRUGS
    DEHAEN, P
    NEW YORK STATE JOURNAL OF MEDICINE, 1969, 69 (24) : 3157 - &
  • [4] Mesitylcopper - A Powerful Tool in Synthetic Chemistry
    Stollenz, Michael
    Meyer, Franc
    ORGANOMETALLICS, 2012, 31 (22) : 7708 - 7727
  • [5] Changing synthetic requirements in medicinal chemistry
    Martin, Nathaniel G.
    ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY, 2012, 243
  • [6] Expanding the medicinal chemistry synthetic toolbox
    Bostrom, Jonas
    Brown, Dean G.
    Young, Robert J.
    Keseru, Gyorgy M.
    NATURE REVIEWS DRUG DISCOVERY, 2018, 17 (10) : 709 - 727
  • [7] Expanding the medicinal chemistry synthetic toolbox
    Jonas Boström
    Dean G. Brown
    Robert J. Young
    György M. Keserü
    Nature Reviews Drug Discovery, 2018, 17 : 709 - 727
  • [8] Boron medicinal chemistry and synthetic aspects
    Ahmet, Jonathan T.
    Spencer, John
    FUTURE MEDICINAL CHEMISTRY, 2013, 5 (06) : 621 - 622
  • [9] Synthetic and medicinal chemistry of trifluoromethyl ketones
    Kawase, M
    JOURNAL OF SYNTHETIC ORGANIC CHEMISTRY JAPAN, 2001, 59 (08) : 755 - 765
  • [10] Synthetic Medicinal Chemistry of the Biomolecular Components Mimics
    Takahata, Hiroki
    YAKUGAKU ZASSHI-JOURNAL OF THE PHARMACEUTICAL SOCIETY OF JAPAN, 2013, 133 (05): : 575 - 585
12345