TRANSPLANTATION BENEFIT of belatacept: kidney transplantation moves forward

被引：9

作者：

Naesens, Maarten ^{[1
]}

Thaunat, Olivier ^{[2
]}

机构：

[1] KU Leuven Univ Leuven, Dept Microbiol & Immunol, Herestr 49, B-3000 Leuven, Belgium

[2] Hop Edouard Herriot, HCL, Dept Transplantat Nephrol & Clin Immunol, 5 Pl Arsonval, F-69003 Lyon, France

来源：

NATURE REVIEWS NEPHROLOGY | 2016年 / 12卷 / 05期

关键词：

PHASE-III; CYCLOSPORINE; RECIPIENTS; EXTENSION;

D O I：

10.1038/nrneph.2016.34

中图分类号：

R5 [内科学]; R69 [泌尿科学（泌尿生殖系疾病）];

学科分类号：

1002 ; 100201 ;

摘要：

New data from the BENEFIT study demonstrate that belatacept improves long-term allograft and patient survival after kidney transplantation, despite higher rates of biopsy-proven acute rejection than with ciclosporin. The noninferiority design of BENEFIT represents a feasible strategy to further the development of innovator drugs to reduce late graft loss.

引用

页码：261 / 262

页数：2

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