Adipose tissue autophagy status in obesity: Expression and flux-two faces of the picture

被引:35
|
作者
Soussi, Hedi [1 ]
Clement, Karine [1 ]
Dugail, Isabelle [1 ]
机构
[1] Univ Paris 04, INSERM UMRS 1166, Inst Cardiometab & Nutr, Pitie Salpetriere Hosp, Paris, France
关键词
adipocyte; bariatric surgery; DAPK2; LC3-II; obesity;
D O I
10.1080/15548627.2015.1106667
中图分类号
Q2 [细胞生物学];
学科分类号
071009 ; 090102 ;
摘要
In the context of elevated prevalence of obesity-associated metabolic diseases in the human population wordwide, interest in the autophagy degradation pathway is increasing, due to close links with energy metabolism, nutritional state, and inflammation. Here we highlight recent data focusing on adipose tissue which demonstrate alterations in fat cell autophagic flux in human obesity.
引用
收藏
页码:588 / 589
页数:2
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