Rapid and practical synthesis of D-myo-inositol 1,4,5-trisphosphate

被引:30
|
作者
Garrett, SW [1 ]
Liu, CS [1 ]
Riley, AM [1 ]
Potter, BVL [1 ]
机构
[1] Univ Bath, Dept Pharm & Pharmacol, Wolfson Lab Med Chem, Bath BA2 7AY, Avon, England
关键词
D O I
10.1039/a801874j
中图分类号
O62 [有机化学];
学科分类号
070303 ; 081704 ;
摘要
A concise synthetic sequence to biologically active D-myo-inositol 1,4,5-trisphosphate is described involving just five steps from myo-inositol and minimal chromatography with a key transformation of orthoacetate into acetate protection.
引用
收藏
页码:1367 / 1368
页数:2
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