Orientation analysis of collagen fibers in healing tendon by using second-harmonic-generation microscopy

被引:0
|
作者
Hase, E. [1 ]
Minamikawa, T. [1 ]
Sato, K. [1 ]
Yonekura, D. [1 ]
Takahashi, M. [2 ]
Yasui, T. [1 ]
机构
[1] Tokushima Univ, 2-1 Minami Josanjima, Tokushima 7708506, Japan
[2] Tokushima Prefectural Cent Hosp, 1-10-3 Kuramoto, Tokushima 7708539, Japan
关键词
Second-harmonic-generation; collagen; tendon; healing; ACHILLES-TENDON; DAMAGE; RUPTURE; MODEL;
D O I
10.1117/12.2251111
中图分类号
TH742 [显微镜];
学科分类号
摘要
Tendon rupture is a trauma that is difficult to fully recover from. Therefore, non-destructive and non-invasive evaluation method for the tendon healing is strongly required. In this study, we performed the orientation analysis of collagen fiber in healing tendon by two-dimensional Fourier transform (2D-FT) of SHG image. The extracted 2D-FT power spectra imply the correlation with the degree of the tendon healing. These results indicate that SHG microscopy has a unique potential as a non-destructive and non-invasive indicator of tendon healing.
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页数:6
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