Inflammatory arthritis in patients with COVID-19

被引:11
|
作者
Conway, Richard
Konig, Maximilian F.
Graef, Elizabeth R.
Webb, Kate
Yazdany, Jinoos
Kim, Alfred H. J.
机构
[1] St James Hosp, Dept Rheumatol, Dublin, Ireland
[2] Johns Hopkins Univ, Sch Med, Dept Med, Div Rheumatol, Baltimore, MD 21205 USA
[3] COVID 19 Global Rheumatol Alliance, Boston, MA USA
[4] Univ Cape Town, Sch Child & Adolescent Hlth, Red Cross War Mem Childrens Hosp, Div Paediat Rheumatol, Cape Town, South Africa
[5] Francis Crick Inst, Crick African Network, London, England
[6] Univ Calif San Francisco, Dept Med, Zuckerberg San Francisco Gen Hosp, Div Rheumatol, San Francisco, CA 94143 USA
[7] Washington Univ, Sch Med, Dept Med, Div Rheumatol, St Louis, MO 63110 USA
关键词
SYSTEMIC-LUPUS-ERYTHEMATOSUS; HUMAN-IMMUNODEFICIENCY-VIRUS; CORONAVIRUS DISEASE 2019; RHEUMATIC-DISEASES; CLINICAL-COURSE; SYNOVIAL-FLUID; COMPLEMENT; INFECTION; ACTIVATION; ADULT;
D O I
10.1016/j.trsl.2021.02.010
中图分类号
R446 [实验室诊断]; R-33 [实验医学、医学实验];
学科分类号
1001 ;
摘要
Patients with inflammatory arthritis represent a possible high-risk group to COVID-19 due to their immunosuppressive regimen designed to maintain low disease activity. Thus, substantial effort has been put forth to understand the impact of COVID-19 on these patients. Patients with rheumatic diseases as a whole do not appear to be more susceptible to acquiring COVID-19. Furthermore, immunosuppression generally did not increase the likelihood of developing severe COVID-19, with the important exception of medium and high-dose glucocorticoid use. In addition, a small number of COVID-19 patients have developed new inflammatory arthritis; whether this represents an unmasking of previous subclinical disease or a bone fide virus induced arthritis is unclear. Nevertheless, it appears that inflammatory arthritis patients currently on immunosuppression should continue their medication to prevent future flares and limit glucocorticoid usage. While this continues to be a rapidly evolving field, these data are reassuring to both patients with and providers treating inflammatory arthritides.
引用
收藏
页码:49 / 59
页数:11
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