机构:
Yale Univ, Sch Med, Dept Immunobiol, New Haven, CT 06520 USA
Yale Univ, Sch Med, Howard Hughes Med Inst, New Haven, CT 06520 USAYale Univ, Sch Med, Dept Immunobiol, New Haven, CT 06520 USA
Medzhitov, Ruslan
[1
,2
]
机构:
[1] Yale Univ, Sch Med, Dept Immunobiol, New Haven, CT 06520 USA
[2] Yale Univ, Sch Med, Howard Hughes Med Inst, New Haven, CT 06520 USA
Inflammation is an essential immune response that enables survival during infection or injury and maintains tissue homeostasis under a variety of noxious conditions. Inflammation comes at the cost of a transient decline in tissue function, which can in turn contribute to the pathogenesis of diseases of altered homeostasis.