Exocrine pancreatic insufficiency in type 1 and type 2 diabetes mellitus: do we need to treat it? A systematic review

被引：28
|
作者：
Zsori, Gabor [1 ]
Illes, Dora [1 ]
Terzin, Viktoria [1 ]
Ivany, Emese [1 ]
Czako, Laszlo [1 ]
机构：
[1] Univ Szeged, Fac Med, Albert Szent Gyorgyi Med & Pharmaceut Ctr, Dept Med 1, Koranyi Fasor 8-10, H-6720 Szeged, Hungary
来源：
PANCREATOLOGY | 2018年 / 18卷 / 05期
关键词：
Diabetes mellitus; Pancreatic enzyme replacement therapy; Pancreatic exocrine insufficiency; Steatorrhea; FECAL ELASTASE-1 CONCENTRATIONS; HIGH PREVALENCE; GASTROINTESTINAL SYMPTOMS; BREATH TEST; INSULIN; THERAPY; METABOLISM; SECRETION; ENDOCRINE; VOLUME;
D O I：
10.1016/j.pan.2018.05.006
中图分类号：
R57 [消化系及腹部疾病];
学科分类号：
摘要：
The exocrine and endocrine pancreata are very closely linked both anatomically and physiologically. Abdominal symptoms such as nausea, bloating, diarrhea, steatorrhea, and weight loss can often occur in diabetic patients. Impairments of the exocrine pancreatic function seem to be a frequent complication of diabetes mellitus; however, they are largely overlooked. The aim of this paper is to provide an overview of the current concepts of exocrine pancreatic insufficiency (PEI) in diabetes mellitus. The prevalence and symptoms of PEI in diabetes mellitus, the pathomechanism, and difficulties of diagnosis and therapy of PEI are summarized in this systematic review. (C) 2018 IAP and EPC. Published by Elsevier B.V. All rights reserved.
引用
收藏
页码：559 / 565
页数：7
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