Pharmacokinetics and biodistribution of idursulfase in non-human primates after intrathecal-lumbar administration

被引：0
|
作者：
Chung, Jou-Ku [1 ]
Mascelli, Mary Ann [1 ]
McCauley, Thomas [1 ]
机构：
[1] Shire, Lexington, MA USA
来源：
MOLECULAR GENETICS AND METABOLISM | 2015年 / 114卷 / 02期
关键词：
D O I：
10.1016/j.ymgme.2014.12.053
中图分类号：
R5 [内科学];
学科分类号：
1002 ; 100201 ;
摘要：
51
引用
收藏
页码：S31 / S32
页数：2
相关论文
共 50 条
  • [1] PHARMACOKINETICS AND BIODISTRIBUTION OF IDURSULFASE IN CYNOMOLGUS MONKEYS AFTER INTRATHECAL-LUMBAR ADMINISTRATION
    Chung, J.
    Xie, H.
    Mascelli, M.
    McCauley, T.
    [J]. CLINICAL PHARMACOLOGY & THERAPEUTICS, 2013, 93 : S38 - S38
  • [2] Biodistribution of idursulfase in cynomolgus monkeys after intrathecal-lumbar administration
    Chung, Jou-Ku
    Brown, Eilish
    Crooker, Robert
    Palmieri, Kathleen J.
    McCauley, Thomas G.
    [J]. MOLECULAR GENETICS AND METABOLISM, 2016, 117 (02) : S35 - S35
  • [3] Biodistribution of Idursulfase Formulated for Intrathecal Use (Idursulfase-IT) in Cynomolgus Monkeys after Intrathecal Lumbar Administration
    Chung, Jou-Ku
    Brown, Eilish
    Crooker, Bob
    Palmieri, Kathleen J.
    McCauley, Thomas G.
    [J]. PLOS ONE, 2016, 11 (10):
  • [4] PET imaging of enzyme delivery to the brain through lumbar intrathecal administration in non-human primates
    Papisov, Mikhail
    Belov, Vasily
    Fischman, Alan
    McCauley, Thomas
    Heartlein, Michael
    Calias, Pericles
    [J]. JOURNAL OF NUCLEAR MEDICINE, 2011, 52
  • [5] Vector Biodistribution After Recombinant AAVrh10 Intrathecal Delivery in Non-Human Primates
    Gernoux, Gwladys
    Borel, Florie
    Gao, Guangping
    Brown, Robert H.
    Mueller, Christian
    [J]. MOLECULAR THERAPY, 2016, 24 : S39 - S39
  • [6] Plasma and cerebrospinal fluid pharmacokinetics of imatinib after administration to non-human primates.
    Neville, K
    Parise, RA
    Blaney, SM
    Thompson, P
    Aleksic, A
    Egorin, MJ
    Balis, FM
    McGuffey, L
    McCully, C
    Berg, SL
    [J]. CLINICAL PHARMACOLOGY & THERAPEUTICS, 2004, 75 (02) : P59 - P59
  • [7] The plasma and cerebrospinal fluid pharmacokinetics of satraplatin after intravenous administration in non-human primates
    Marcus, Leigh J.
    Murphy, Robert F.
    Fox, Elizabeth
    McCully, Cynthia L.
    Cruz, Rafeal
    Warren, Kathy
    Balis, Frank M.
    Widemann, Brigitte C.
    Meyer, Thorsten
    [J]. CANCER RESEARCH, 2010, 70
  • [8] The plasma and cerebrospinal fluid pharmacokinetics of sorafenib after intravenous administration in non-human primates
    AeRang Kim
    Cindy McCully
    Rafael Cruz
    Diane E. Cole
    Elizabeth Fox
    Frank M. Balis
    Brigitte C. Widemann
    [J]. Investigational New Drugs, 2012, 30 : 524 - 528
  • [9] The serum and cerebrospinal fluid pharmacokinetics of anakinra after intravenous administration to non-human primates
    Fox, Elizabeth
    Jayaprakash, Nalini
    Pham, Tuyet-Hang
    Rowley, Ayana
    McCully, Cynthia L.
    Pucino, Frank
    Goldbach-Mansky, Raphaela
    [J]. JOURNAL OF NEUROIMMUNOLOGY, 2010, 223 (1-2) : 138 - 140
  • [10] Plasma and cerebrospinal fluid pharmacokinetics of pemetrexed after intravenous administration in non-human primates
    Stacie L. Stapleton
    Joel M. Reid
    Patrick A. Thompson
    Matthew M. Ames
    Renee M. McGovern
    Leticia McGuffey
    Jed Nuchtern
    Robert Dauser
    Susan M. Blaney
    [J]. Cancer Chemotherapy and Pharmacology, 2007, 59 : 461 - 466
12345