Up-regulation of the multidrug resistance gene Mdr1b by NF-KB in vitro and in vivo.

被引:0
|
作者
Ros, JE
Geuken, M
Kuehnel, F
Schuetz, JD
Jansen, PLM
Trautwein, C
Muller, M
机构
[1] Univ Groningen, Div Gastroenterol & Hepatol, Groningen, Netherlands
[2] Hannover Med Sch, Dept Gastroenterol & Hepatol, D-3000 Hannover, Germany
[3] St Jude Childrens Res Hosp, Memphis, TN 38105 USA
[4] Acad Hosp Groningen, Groningen, Netherlands
[5] Med Hsch Hannover, Hannover, Germany
关键词
D O I
暂无
中图分类号
R57 [消化系及腹部疾病];
学科分类号
摘要
1114
引用
收藏
页码:438A / 438A
页数:1
相关论文
共 50 条
  • [1] TNF-α mediated up-regulation of the multidrug resistance gene mdr1b but not of mrp1 in rat hepatocytes is dependent on NF-κB activation
    Ros, JE
    Geuken, M
    Schuetz, JD
    Koning, H
    Kuipers, F
    Manns, MP
    Moshage, H
    Jansen, PL
    Trautwein, C
    Muller, M
    HEPATOLOGY, 1999, 30 (04) : 462A - 462A
  • [2] PROGESTERONE REGULATES THE MURINE MULTIDRUG RESISTANCE MDR1B GENE
    PIEKARZ, RL
    COHEN, D
    HORWITZ, SB
    JOURNAL OF BIOLOGICAL CHEMISTRY, 1993, 268 (11) : 7613 - 7616
  • [3] Transcriptional regulation of the murine multidrug resistance gene mdr1b by progesterone occurs via an indirect mechanism
    Mallick, S
    Horwitz, SB
    DNA AND CELL BIOLOGY, 1997, 16 (07) : 807 - 818
  • [4] REGULATION OF MULTIDRUG-RESISTANCE GENE MDR1B/MDR1 EXPRESSION IN ISOLATED MOUSE UTERINE EPITHELIAL-CELLS
    KUO, MT
    JULIAN, JA
    HUSAIN, F
    SONG, RD
    CARSON, DD
    JOURNAL OF CELLULAR PHYSIOLOGY, 1995, 164 (01) : 132 - 141
  • [5] CAMP and protein kinase A activation participate in Mdr1B up-regulation in primary rat hepatocytes
    Ziemann, C
    Riecke, A
    Rüdell, G
    Hirsch-Ernst, KI
    Kahl, GF
    NAUNYN-SCHMIEDEBERGS ARCHIVES OF PHARMACOLOGY, 2002, 365 : R151 - R151
  • [6] Curcumin down-regulates the multidrug-resistance mdr1b gene by inhibiting the PI3K/Akt/NFκB pathway
    Choi, Byeong Hyeok
    Kim, Chang Gun
    Lim, Yoongho
    Shin, Soon Young
    Lee, Young Han
    CANCER LETTERS, 2008, 259 (01) : 111 - 118
  • [7] Bromocriptine transcriptionally activates the multidrug resistance gene (pgp2/mdr1b) by a novel pathway
    Furuya, KN
    Thottassery, JV
    Schuetz, EG
    Sharif, M
    Schuetz, JD
    JOURNAL OF BIOLOGICAL CHEMISTRY, 1997, 272 (17) : 11518 - 11525
  • [8] Up-regulation of the multidrug resistance genes, mrp1 and mdr1b, and down regulation of the organic anion transporter, mrp2, and the bile salt transporter, spgp, in endotoxemic rat liver
    Vos, T
    Hooiveld, GJE
    Konong, H
    Childs, S
    Meijer, DKF
    Moshage, H
    Jansen, PLM
    Muller, M
    HEPATOLOGY, 2006, 43 (02) : S9 - S11
  • [9] HSF-1 Knockout Induces Multidrug Resistance Gene (MDR1b) and Enhances Drug Extrusion in the Heart
    Krishnamurthy, Karthikeyan
    Vedam, Kaushik
    Kanagasabai, Ragu
    Druhan, Lawrence J.
    Ilangovan, Govindasamy
    CIRCULATION RESEARCH, 2012, 111 (04)
  • [10] Phytochemicals and Regulation of NF-kB in Inflammatory Bowel Diseases: An Overview of In Vitro and In Vivo Effects
    Laurindo, Lucas Fornari
    dos Santos, Ana Rita de Oliveira
    de Carvalho, Antonelly Cassio Alves
    Bechara, Marcelo Dib
    Guiguer, Elen Landgraf
    Goulart, Ricardo de Alvares
    Sinatora, Renata Vargas
    Araujo, Adriano Cressoni
    Barbalho, Sandra Maria
    METABOLITES, 2023, 13 (01)