Endothelial cell culture: beginnings of modern vascular biology

被引:58
|
作者
Nachman, RL
Jaffe, EA
机构
[1] Cornell Univ, Weill Med Coll, Dept Med, New York, NY 10021 USA
[2] Interfaith Med Ctr, Dept Med, Brooklyn, NY USA
来源
JOURNAL OF CLINICAL INVESTIGATION | 2004年 / 114卷 / 08期
关键词
D O I
10.1172/JCI200423284
中图分类号
R-3 [医学研究方法]; R3 [基础医学];
学科分类号
1001 ;
摘要
Endothelial cells derived from human umbilical veins were first successfully cultured in vitro in 1973. Weibel-Palade bodies and the von Willebrand factor antigen were used as morphological, immunohistochemical,and functional markers to unequivocally identify the cells. These landmark studies helped initiate the growth of modern vascular biology.
引用
收藏
页码:1037 / 1040
页数:4
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