PREPARATION OF A BIS-MEM ASCORBIC ACID-LIPOIC ACID CONJUGATE

被引：0
|
作者：
Amin, Rasidul [1 ]
Hunt, David A. [2 ]
机构：
[1] Symmetry Biosci, 112 Nova Dr,Suite 1, Morrisville, NC 27560 USA
[2] Coll New Jersey, Dept Chem, 2000 Pennington Rd, Ewing, NJ 08628 USA
来源：
HETEROCYCLIC LETTERS | 2022年 / 12卷 / 02期
关键词：
Ascorbic acid; lipoic acid; conjugation;
D O I：
10.1470/j.rter.487.0187
中图分类号：
O62 [有机化学];
学科分类号：
070303 ; 081704 ;
摘要：
The preparation of a bis-MEM ascorbic acid-lipoic acid conjugate in support of pharmacodynamic and pharmacokinetic studies has been achieved through a four-step convergent synthesis.
引用
收藏
页码：239 / 242
页数：4
相关论文
共 50 条
  • [1] PREPARATION OF A RESVERATROL-ASCORBIC ACID MEM CONJUGATE
    Amin, Rasidul
    Hunt, David A.
    HETEROCYCLIC LETTERS, 2022, 12 (01): : 13 - 18
  • [2] At low doses, a γ-linolenic acid-lipoic acid conjugate is more effective than docosahexaenoic acid-enriched phospholipids in preventing neuropathy in diabetic rats
    Pitel, Severine
    Raccah, Denis
    Gerbi, Alain
    Pieroni, Gerard
    Vague, Philippe
    Coste, Thierry C.
    JOURNAL OF NUTRITION, 2007, 137 (02): : 368 - 372
  • [3] Preparation of α-lipoic acid/chitosan microparticle conjugate and its in vitro antioxidative activity
    Vidovic, Bojana
    Milasinovic, Nikola
    Vidovic, Jana
    Calija, Bojan
    Sakac, Milkica Crevar
    Vujic, Zorica
    Milic, Jela
    Dordevic, Brizita
    Krusic, Melina Kalagasidis
    Knezevic-Jugovic, Zorica
    ANNALS OF NUTRITION AND METABOLISM, 2015, 67 : 484 - 485
  • [4] SYNTHETIC PREPARATION OF LIPOIC ACID
    HORNBERGER, CS
    HEITMILLER, RF
    GUNSALUS, IC
    SCHNAKENBERG, GHF
    REED, LJ
    JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 1952, 74 (09) : 2382 - 2382
  • [5] The effect of gamma-linolenic acid-lipoic acid on functional deficits in the central nervous system in diabetic rats
    Smale, SE
    Biessels, GJ
    Duis, SEJ
    Kamal, A
    Gispen, WH
    DIABETOLOGIA, 1999, 42 : A293 - A293
  • [6] Preparation and Characterization of Self-aggregated Nanoparticles of Chitosan-Lipoic Acid Conjugate
    Park, Eun Ju
    Kim, Young Jin
    POLYMER-KOREA, 2008, 32 (06) : 544 - 548
  • [7] Inhibition of Human Amylin Aggregation and Cellular Toxicity by Lipoic Acid and Ascorbic Acid
    Azzam, Sarah Kassem
    Jang, Hyunwoo
    Choi, Myung Chul
    Alsafari, Habiba
    Lukman, Suryani
    Lee, Sungmun
    MOLECULAR PHARMACEUTICS, 2018, 15 (06) : 2098 - 2106
  • [8] PREPARATION AND ASSAY OF LIPOIC ACID AND DERIVATIVES
    GUNSALUS, IC
    RAZZELL, WE
    METHODS IN ENZYMOLOGY, 1957, 3 : 941 - 946
  • [9] α-lipoic acid enhances reduced glutathione, ascorbic acid, and α-tocopherol in aged rats
    Arivazhagan, P
    Shila, S
    Narchonai, E
    Panneerselvam, C
    JOURNAL OF ANTI-AGING MEDICINE, 2002, 5 (03): : 265 - 269
  • [10] Preparation and characterization of a covalent edge-functionalized lipoic acid-MoS2 conjugate
    Jeong, Misoon
    Kim, Somin
    Ju, Sang-Yong
    RSC ADVANCES, 2016, 6 (43) : 36248 - 36255
12345