Neuroanatomical variation in autism spectrum disorder: A comprehensive review

被引：10

作者：

Jumah, Fareed ^{[1
]}

Ghannam, Malik ^{[1
]}

Jaber, Mohammad ^{[1
]}

Adeeb, Nimer ^{[2
]}

Tubbs, R. Shane ^{[3
]}

机构：

[1] An Najah Natl Univ Hosp, Dept Neurosci, Nablus, Palestine

[2] Harvard Univ, Beth Israel Deaconess Med Ctr, Sch Med, Dept Neurosurg, Boston, MA 02215 USA

[3] Seattle Sci Fdn, Seattle, WA USA

来源：

CLINICAL ANATOMY | 2016年 / 29卷 / 04期

关键词：

autism; anatomical; variations; brain; neuroanatomy; VOXEL-BASED MORPHOMETRY; HIGH-FUNCTIONING AUTISM; CORTICAL THICKNESS ANALYSIS; CORPUS-CALLOSUM; WHITE-MATTER; HEAD CIRCUMFERENCE; POSTERIOR-FOSSA; CEREBELLAR VERMIS; BRAIN STRUCTURE; MENTAL-RETARDATION;

D O I：

10.1002/ca.22717

中图分类号：

R602 [外科病理学、解剖学]; R32 [人体形态学];

学科分类号：

100101 ;

摘要：

Autism Spectrum Disorder (ASD) is a neurodevelopmental disorder characterized by impairments in socialization, communication, and behavior. Many investigators have described the anatomical abnormalities in autistic brains, in an attempt to correlate them with the manifestations of ASD. Herein, we reviewed all the available literature about the neuroanatomical findings in ASD available via PubMed and Google Scholar. References found in review articles were also searched manually. There was substantial discrepancy throughout the literature regarding the reported presence and significance of neuroanatomical findings in ASD, and this is thoroughly discussed in the present review. Clin. Anat. 29:454-465, 2016. (c) 2016 Wiley Periodicals, Inc.

引用

页码：454 / 465

页数：12

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