Recurrent brief depressive disorder reinvestigated: a community sample of adolescents and young adults

被引:23
|
作者
Pezawas, L
Wittchen, HU
Pfister, H
Angst, J
Lieb, R
Kasper, S
机构
[1] NIMH, CBDB, NIH, Bethesda, MD 20892 USA
[2] Univ Vienna, Dept Gen Psychiat, A-1010 Vienna, Austria
[3] Tech Univ Dresden, D-8027 Dresden, Germany
[4] Max Planck Inst Psychiat, Dept Clin Psychol & Epidemiol, D-80804 Munich, Germany
[5] Univ Zurich, Univ Hosp Psychiat, Zurich, Switzerland
关键词
D O I
10.1017/S0033291702006967
中图分类号
B849 [应用心理学];
学科分类号
040203 ;
摘要
Background. This article presents prospective lower bound estimations of findings on prevalence, incidence, clinical correlates, severity markers, co-morbidity and course stability of threshold and subthreshold recurrent brief depressive disorder (RBD) and other mood disorders in a community sample of 3021 adolescents. Method. Data were collected at baseline (age 14-17) and at two follow-up interviews within an assessment was based on the Munich Composite observation period of 42 months. Diagnostic International Diagnostic Interview (M-CIDI). Results. Our data suggest that RBD is a prevalent (2(.)6%) clinical condition among depressive disorders (21(.)3 %) being at least as prevalent as dysthymia (2(.)3 %) in young adults over lifetime. Furthermore, RBD is associated with significant clinical impairment sharing many features with major depressive disorder (MDD). Suicide attempts were reported in 7(.)8 % of RBD patients, which was similar to MDD (11(.)9 %). However, other features, like gender distribution or co-morbidity patterns, differ essentially from MDD. Furthermore, the lifetime co-occurrence of MDD and RBD or combined depression represents a severe psychiatric condition. Conclusions. This study provides further independent support for RBD as a clinically significant syndrome that could not be significantly explained as a prodrome or residual of major affective disorders.
引用
收藏
页码:407 / 418
页数:12
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