A simple solid phase diversity linker strategy using enol phosphonates

被引：22
|
作者：
Campbell, IB
Guo, J
Jones, E
Steel, PG
机构：
[1] Univ Durham, Dept Chem, Sci Labs, Durham DH1 3LE, England
[2] GlaxoSmithKline, Stevenage SG1 2NY, Herts, England
来源：
ORGANIC & BIOMOLECULAR CHEMISTRY | 2004年 / 2卷 / 19期
关键词：
D O I：
10.1039/b411111g
中图分类号：
O62 [有机化学];
学科分类号：
070303 ; 081704 ;
摘要：
Polymer bound lactam enol phosphonates can be easily generated using simple phenol on polystyrene resin. These stable, storable compounds can be released in a diversity cleavage strategy, using Suzuki cross coupling conditions, to provide 2-arylenamides in moderate to good overall yields.
引用
收藏
页码：2725 / 2727
页数：3
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