As part of a retrospective study, 1775 patients, who were treated in 1991 and 1992 in the operative ICU for a minimum of three days, were examined regularly regarding methicillin resistant S. aureus (MRSA) and the consequences thereof. An analysis of the data (age, sex, previous illness, length of hospital stay before the ICU, antibiotics before the ICU, invasive diagnostic process, immunosuppressives, diagnosis at admittance) showed no significant statistical risk of MRSA. An almost constant probability of MRSA detection during the ICU stay was shown. Patients with MRSA had a significantly higher mortality rate and frequent septic complications. The incidence of MRSA in operative intensive care medicine increases the rate of complications, mortality and costs. The most important counter measures are strict hygiene and early specific chemotherapy.
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Royal Prince Alfred Hosp, Dept Infect Dis, Sydney, NSW, Australia
Royal Prince Alfred Hosp, Dept Microbiol, Sydney, NSW, Australia
Univ Sydney, Fac Med, Sydney, NSW, AustraliaRoyal Prince Alfred Hosp, Dept Infect Dis, Sydney, NSW, Australia
Lee, Andie S.
de Lencastre, Herminia
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Rockefeller Univ, Lab Microbiol & Infect Dis, 1230 York Ave, New York, NY 10021 USA
Univ Nova Lisboa, Inst Tecnol Quim & Biol Antonio Xavier, Lab Mol Genet, Oeiras, PortugalRoyal Prince Alfred Hosp, Dept Infect Dis, Sydney, NSW, Australia
de Lencastre, Herminia
Garau, Javier
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Hosp Univ Mutua Terrassa, Dept Med, Barcelona, SpainRoyal Prince Alfred Hosp, Dept Infect Dis, Sydney, NSW, Australia
Garau, Javier
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Kluytmans, Jan
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Malhotra-Kumar, Surbhi
Peschel, Andreas
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Univ Tubingen, Interfac Inst Microbiol & Infect Med, Dept Infect Biol, Tubingen, Germany
German Ctr Infect Res, Partner Site Tubingen, Tubingen, GermanyRoyal Prince Alfred Hosp, Dept Infect Dis, Sydney, NSW, Australia
Peschel, Andreas
Harbarth, Stephan
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Univ Geneva Hosp, Infect Control Programme, Geneva, Switzerland
WHO Collaborating Ctr, Fac Med, Geneva, SwitzerlandRoyal Prince Alfred Hosp, Dept Infect Dis, Sydney, NSW, Australia
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S Western Area Pathol Serv, Dept Microbiol & Infect Dis, Liverpool, NSW, AustraliaS Western Area Pathol Serv, Dept Microbiol & Infect Dis, Liverpool, NSW, Australia
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Ctr Dis Control & Prevent, Div Healthcare Qual Promot, Atlanta, GA 30333 USACtr Dis Control & Prevent, Div Healthcare Qual Promot, Atlanta, GA 30333 USA
Tenover, FC
Pearson, ML
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Ctr Dis Control & Prevent, Div Healthcare Qual Promot, Atlanta, GA 30333 USACtr Dis Control & Prevent, Div Healthcare Qual Promot, Atlanta, GA 30333 USA