Early detection of prostate cancer in German urological practice by digital rectal examination and prostate-specific antigen

被引：0

作者：

Luboldt, HJ ^{[1
]}

Hüsing, J ^{[1
]}

Rübben, H ^{[1
]}

Altwein, JE ^{[1
]}

Bichler, KH ^{[1
]}

Czaja, D ^{[1
]}

Fornara, P ^{[1
]}

Jöckel, KH ^{[1
]}

Schalkhäuser, K ^{[1
]}

Weissbach, L ^{[1
]}

Wirth, M ^{[1
]}

机构：

[1] Univ Essen Gesamthsch, Inst Med Informat Epidemiol & Biometrie, Urol Klin & Poliklin, D-45122 Essen, Germany

来源：

UROLOGE A | 2000年 / 39卷 / 04期

关键词：

prostate cancer; early detection; PSA; positive predictive value;

D O I：

10.1007/s001200050365

中图分类号：

R5 [内科学]; R69 [泌尿科学（泌尿生殖系疾病）];

学科分类号：

1002 ; 100201 ;

摘要：

For the early detection of prostate cancer, a patient should undergo digital rectal examination (DRE) and PSA investigation. Followup of increased PSA levels detects nearly 80% of cancers. Positive predictive value of suspicious DRE and PSA is about 50%. Whereas in the first evaluation of this case-finding trial about 70% of the patients had organ-confined cancers, nearly all of the detected cancers in the follow-up investigation were organ confined. The increased number of organ-confined cancers detected in early periodical examinations can lead to a reduction of mortality and morbidity from prostate cancer.

引用

页码：330 / 333

页数：4

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