Solitary pulmonary nodule;
Diagnoses and examination;
Early diagnosis of cancer;
Bronchoscopy;
Lung cancer;
YIELD;
SAFETY;
D O I:
10.1016/j.rmr.2019.06.008
中图分类号:
R56 [呼吸系及胸部疾病];
学科分类号:
摘要:
Introduction. - Electromagnetic navigation bronchoscopy (ENB) is a recent, minimally invasive procedure utilized to guide endoscopic diagnostic tools to peripheral pulmonary nodules. The place of this technology among other diagnostic procedures remains uncertain. Method. - We analyzed our 30 first months of ENB used in the diagnosis of 106 lesions in 101 patients, from June 2016 to December 2018. Follow-up and final diagnosis was completed for 95 lesions (90%). Results. - ENB was performed for 3.5% of all patients referred for abnormal findings on pulmonary imaging, and represented 19% of second line procedures for peripheral pulmonary lesions. Procedures were performed under general anesthesia, with a mean duration of 35 min. The sensitivity of ENB was 64% (95%Cl: 52-74%) for lesions with a mean diameter of 21 mm, with an improvement over time (sensitivity 69% in the last 18 months). The presence of a bronchus within the lesion (bronchus sign) was associated with an increased sensitivity of 74%. Pneumothorax occurred in 5 patients (5%) of which 4 required drainage. There was no hemoptysis, and no death related to the procedure. Conclusion. - ENB is a minimally invasive procedure reaching acceptable sensitivity in the most difficult patients. ENB can be recommended for the diagnosis of peripheral pulmonary nodules when no other procedure is successful or possible. Its use as a first choice procedure is, for the moment, limited by the cost, but must be weighed against that of non-diagnostic procedures, and the cost of complications of trans-thoracic lung biopsies. (C) 2019 SPLF. Published by Elsevier Masson SAS. All rights reserved.
机构:
MercyOne Moines Med Ctr, Div Pulm & Crit Care, Des Moines, IA USAMercyOne Moines Med Ctr, Div Pulm & Crit Care, Des Moines, IA USA
Greco, Anthony
Smith, Clarissa B.
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机构:
Univ Kansas Hlth Syst, Dept Internal Med, Kansas City, KS USA
3901 Rainbow Blvd, Kansas City, KS 66160 USAMercyOne Moines Med Ctr, Div Pulm & Crit Care, Des Moines, IA USA
Smith, Clarissa B.
Shi, Xiaosong
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机构:
Univ Kansas Hlth Syst, Div Pulm Crit Care & Sleep Med, Kansas City, KS USAMercyOne Moines Med Ctr, Div Pulm & Crit Care, Des Moines, IA USA
Shi, Xiaosong
Postigo, Maykol
论文数: 0引用数: 0
h-index: 0
机构:
Univ Kansas Hlth Syst, Div Pulm Crit Care & Sleep Med, Kansas City, KS USAMercyOne Moines Med Ctr, Div Pulm & Crit Care, Des Moines, IA USA