Responses of hepatic biochemical markers in bream Abramis brama L. to dietary administered polychlorinated biphenyls

An experimental study of the effects of dietary administered polychlorinated biphenyls (PCBs) on bream (Abramis brama L.) is reported in the present article. Responses of xenobiotic biotransformation system (ethoxyresorufin-O-deethylase and glutathione-S-transferase activities), antioxidant system (superoxide dismutase and catalase activities), and lipid peroxidation system (levels of conjugated dienes and malonic dialdehyde) are investigated. A PCB dose of 2 mg/kg feed does not cause irreversible physiological transformations in bream after 14 days of administration. The defense systems appear to efficiently suppress the effects of the xenobiotic and maintain stable and low intensity of the destructive processes at the exposure conditions used.