Treatment of visceral leishmaniasis with injectable paromomycin (aminosidine). An open-label randomized phase-II clinical study

被引:49
|
作者
Thakur, CP
Kanyok, TP
Pandey, AK
Sinha, GP
Messick, C
Olliaro, P
机构
[1] WHO, TDR, World Bank,Prod Dev, UNDP,Special Programme Res & Training Trop Dis, CH-1211 Geneva 27, Switzerland
[2] Kalaazar Res Ctr, Patna, Bihar, India
关键词
visceral leishmaniasis; chemotherapy; paromomycin; sodium stibogluconate; clinical trial; India;
D O I
10.1016/S0035-9203(00)90131-7
中图分类号
R1 [预防医学、卫生学];
学科分类号
1004 ; 120402 ;
摘要
[No abstract available]
引用
收藏
页码:432 / 433
页数:2
相关论文
共 50 条
  • [1] Paromomycin for the Treatment of Visceral Leishmaniasis in Sudan: A Randomized, Open-Label, Dose-Finding Study
    Musa, Ahmed M.
    Younis, Brima
    Fadlalla, Ahmed
    Royce, Catherine
    Balasegaram, Manica
    Wasunna, Monique
    Hailu, Asrat
    Edwards, Tansy
    Omollo, Raymond
    Mudawi, Mahmoud
    Kokwaro, Gilbert
    El-Hassan, Ahmed
    Khalil, Eltahir
    [J]. PLOS NEGLECTED TROPICAL DISEASES, 2010, 4 (10)
  • [2] A prospective randomized, comparative, open-label trial of the safety and efficacy of paromomycin (aminosidine) plus sodium stibogluconate versus sodium stibogluconate alone for the treatment of visceral leishmaniasis
    Thakur, CP
    Kanyok, TP
    Pandey, AK
    Sinha, GP
    Zaniewski, AE
    Houlihan, HH
    Olliaro, P
    [J]. TRANSACTIONS OF THE ROYAL SOCIETY OF TROPICAL MEDICINE AND HYGIENE, 2000, 94 (04) : 429 - 431
  • [3] Geographical Variation in the Response of Visceral Leishmaniasis to Paromomycin in East Africa: A Multicentre, Open-Label, Randomized Trial
    Hailu, Asrat
    Musa, Ahmed
    Wasunna, Monique
    Balasegaram, Manica
    Yifru, Sisay
    Mengistu, Getahun
    Hurissa, Zewdu
    Hailu, Workagegnehu
    Weldegebreal, Teklu
    Tesfaye, Samson
    Makonnen, Eyasu
    Khalil, Eltahir
    Ahmed, Osama
    Fadlalla, Ahmed
    El-Hassan, Ahmed
    Raheem, Muzamil
    Mueller, Marius
    Koummuki, Yousif
    Rashid, Juma
    Mbui, Jane
    Mucee, Geoffrey
    Njoroge, Simon
    Manduku, Veronica
    Musibi, Alice
    Mutuma, Geoffrey
    Kirui, Fredrick
    Lodenyo, Hudson
    Mutea, Dedan
    Kirigi, George
    Edwards, Tansy
    Smith, Peter
    Muthami, Lawrence
    Royce, Catherine
    Ellis, Sally
    Alobo, Moses
    Omollo, Raymond
    Kesusu, Josephine
    Owiti, Rhoda
    Kinuthia, John
    [J]. PLOS NEGLECTED TROPICAL DISEASES, 2010, 4 (10)
  • [4] Pharmacokinetics, Safety, and Efficacy of an Allometric Miltefosine Regimen for the Treatment of Visceral Leishmaniasis in Eastern African Children: An Open-label, Phase II Clinical Trial
    Mbui, Jane
    Olobo, Joseph
    Omollo, Raymond
    Solomos, Alexandra
    Kip, Anke E.
    Kirigi, George
    Sagaki, Patrick
    Kimutai, Robert
    Were, Lilian
    Omollo, Truphosa
    Egondi, Thaddaeus W.
    Wasunna, Monique
    Alvar, Jorge
    Dorlo, Thomas P. C.
    Alves, Fabiana
    [J]. CLINICAL INFECTIOUS DISEASES, 2019, 68 (09) : 1530 - 1538
  • [5] TREATMENT OF VISCERAL LEISHMANIASIS (KALA-AZAR) WITH AMINOSIDINE (= PAROMOMYCIN)-ANTIMONIAL COMBINATIONS, A PILOT-STUDY IN BIHAR, INDIA
    THAKUR, CP
    OLLIARO, P
    GOTHOSKAR, S
    BHOWMICK, S
    CHOUDHURY, BK
    PRASAD, S
    KUMAR, M
    VERMA, BB
    [J]. TRANSACTIONS OF THE ROYAL SOCIETY OF TROPICAL MEDICINE AND HYGIENE, 1992, 86 (06) : 615 - 616
  • [6] Inhaled Nitric Oxide as an Adjunctive Treatment for Cerebral Malaria in Children: A Phase II Randomized Open-Label Clinical Trial
    Mwanga-Amumpaire, Juliet
    Carroll, Ryan W.
    Baudin, Elisabeth
    Kemigisha, Elisabeth
    Nampijja, Dorah
    Mworozi, Kenneth
    Santorino, Data
    Nyehangane, Dan
    Nathan, Daniel I.
    De Beaudrap, Pierre
    Etard, Jean-Franois
    Feelisch, Martin
    Fernandez, Bernadette O.
    Berssenbrugge, Annie
    Bangsberg, David
    Bloch, Kenneth D.
    Boum, Yap, II
    Zapol, Warren M.
    [J]. OPEN FORUM INFECTIOUS DISEASES, 2015, 2 (03):
  • [7] Efficacy and Safety of Amphotericin B Emulsion versus Liposomal Formulation in Indian Patients with Visceral Leishmaniasis: A Randomized, Open-Label Study
    Sundar, Shyam
    Pandey, Krishna
    Thakur, Chandreshwar Prasad
    Jha, Tara Kant
    Das, Vidya Nand Ravi
    Verma, Neena
    Lal, Chandra Shekhar
    Verma, Deepak
    Alam, Shahnawaz
    Das, Pradeep
    [J]. PLOS NEGLECTED TROPICAL DISEASES, 2014, 8 (09):
  • [8] Safety and efficacy of paromomycin/miltefosine/liposomal amphotericin B combinations for the treatment of post-kala-azar dermal leishmaniasis in Sudan: A phase II, open label, randomized, parallel arm study
    Younis, Brima Musa
    Mudawi Musa, Ahmed
    Monnerat, Severine
    Saeed, Mohammed Abdelrahim
    Khalil, Eltahir Awad Gasim
    Ahmed, Anas Elbashir
    Ali, Mujahid Ahmed
    Noureldin, Ali
    Ouattara, Gina Muthoni
    Nyakaya, Godfrey M.
    Teshome, Samuel
    Omollo, Truphosa
    Ochieng, Michael
    Egondi, Thaddaeus
    Mmbone, Mildred
    Chu, Wan-Yu
    Dorlo, Thomas P. C.
    Zijlstra, Eduard E.
    Wasunna, Monique
    Alvar, Jorge
    Alves, Fabiana
    [J]. PLOS NEGLECTED TROPICAL DISEASES, 2023, 17 (11):
  • [9] A phase II open-label study of the intravenous administration of homoharringtonine in the treatment of myelodysplastic syndrome
    Daver, N.
    Vega-Ruiz, A.
    Kantarjian, H. M.
    Estrov, Z.
    Ferrajoli, A.
    Kornblau, S.
    Verstovsek, S.
    Garcia-Manero, G.
    Cortes, J. E.
    [J]. EUROPEAN JOURNAL OF CANCER CARE, 2013, 22 (05) : 605 - 611
  • [10] An open-label single-arm phase II study of regorafenib for the treatment of angiosarcoma
    Agulnik, Mark
    Schulte, Brian
    Robinson, Steven
    Hirbe, Angela C.
    Kozak, Kevin
    Chawla, Sant P.
    Attia, Steven
    Rademaker, Alfred
    Zhang, Hui
    Abbinanti, Susan
    Cehic, Rasima
    Monga, Varun
    Milhem, Mohammed
    Okuno, Scott
    Van Tine, Brian A.
    [J]. EUROPEAN JOURNAL OF CANCER, 2021, 154 : 201 - 208