Nickel-Catalyzed C-Alkylation of Nitroalkanes with Unactivated Alkyl Iodides

被引：40
|
作者：
Rezazadeh, Sina [1 ]
Devannah, Vijayarajan [1 ]
Watson, Donald A. [1 ]
机构：
[1] Univ Delaware, Dept Chem & Biochem, Newark, DE 19716 USA
来源：
JOURNAL OF THE AMERICAN CHEMICAL SOCIETY | 2017年 / 139卷 / 24期
关键词：
THERMAL REDOX CATALYSIS; KINETICS; HALIDES; BROMIDES; SUBSTITUTION; ALLYLATION; ESTERS;
D O I：
10.1021/jacs.7b04312
中图分类号：
O6 [化学];
学科分类号：
0703 ;
摘要：
Enabled by nickel catalysis, a mild and general catalytic method for C-alkylation of nitroalkanes with unactivated alkyl iodides is described. Compatible with primary, secondary, and tertiary alkyl iodides; and tolerant of a wide range of functional groups, this method allows rapid access to diverse nitroalkanes.
引用
收藏
页码：8110 / 8113
页数：4
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