SOX8 expression during chick embryogenesis

被引:36
|
作者
Bell, KM [1 ]
Western, PS [1 ]
Sinclair, AH [1 ]
机构
[1] Univ Melbourne, Royal Childrens Hosp, Ctr Hormone Res, Dept Paediat, Parkville, Vic 3052, Australia
基金
英国医学研究理事会;
关键词
SOX genes; SOX8; embryogenesis; dermomyotome; muscle development; enteric neurones; pancreas; neural tube; limb development; chicken embryo; whole-mount in situ hybridization;
D O I
10.1016/S0925-4773(00)00296-3
中图分类号
Q [生物科学];
学科分类号
07 ; 0710 ; 09 ;
摘要
We have isolated the SOX8 gene from the chicken embryo. This gene shows a high degree of sequence homology to SOX9 and SOX10. Detailed analysis of SOX8 expression by whole-mount in situ shows a dynamic and restricted expression pattern during chick development. SOX8 is expressed in the semitic derivative, the dermomyotome, the developing heart, pancreas, enteric neurone system, limb and the neural tube. This is the first detailed expression analysis of SOX8 in any species (C) 2000 Elsevier Science Ireland Ltd. All rights reserved.
引用
收藏
页码:257 / 260
页数:4
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