Nanotoxicology: a personal perspective

被引：25
|
作者：
Holl, Mark M. Banaszak [1 ,2 ]
机构：
[1] Univ Michigan, Chem Dept & Macromol Sci & Engn, Graham Environm Sustainabil Inst, Program Appl Phys, Ann Arbor, MI 48109 USA
[2] Univ Michigan, Chem Dept & Macromol Sci & Engn, Graham Environm Sustainabil Inst, Programs Biophys, Ann Arbor, MI 48109 USA
来源：
WILEY INTERDISCIPLINARY REVIEWS-NANOMEDICINE AND NANOBIOTECHNOLOGY | 2009年 / 1卷 / 04期
关键词：
SUPPORTED LIPID-BILAYERS; IN-VITRO TOXICITY; QUANTUM DOTS; POLYCATIONIC POLYMERS; MULTIVALENT LIGANDS; HOLE FORMATION; NANOPARTICLES; CYTOTOXICITY; DENDRIMERS; CELLS;
D O I：
10.1002/wnan.27
中图分类号：
TB3 [工程材料学];
学科分类号：
0805 ; 080502 ;
摘要：
Nanoparticles arise from a wide variety of natural and man-made sources and have a diverse array of biological, chemical, and physical properties. The toxicity of these particles can be roughly divided into two categories: 1) the enhanced delivery of toxic agents 2) toxicity induced the properties of the particle itself. The use of nanoparticles to provide enhanced delivery of chemotherapeutics is presented followed by a discussion of the size-based effects of electron transfer and physical membrane disruption. (C) 2009 John Wiley & Sons, Inc. WIREs Nanomed Nanobiotechnol 2009 1 353-359
引用
收藏
页码：353 / 359
页数：7
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