Brain imaging correlates of cognitive impairment in depression

被引:42
|
作者
Thomas, Emma J. [1 ]
Elliott, Rebecca [1 ]
机构
[1] Univ Manchester, Neurosci & Psychiat Unit, Manchester M13 9PT, Lancs, England
来源
关键词
depression; cognition; emotion; fMRI; antidepressants; connectivity; ANTERIOR CINGULATE ACTIVATION; LEFT PREFRONTAL ACTIVATION; HAPPY FACIAL EXPRESSIONS; VERBAL FLUENCY TASK; MAJOR DEPRESSION; UNIPOLAR DEPRESSION; NEURAL RESPONSES; ANTIDEPRESSANT TREATMENT; INCREASED AMYGDALA; WORKING-MEMORY;
D O I
10.3389/neuro.09.030.2009
中图分类号
Q189 [神经科学];
学科分类号
071006 ;
摘要
This review briefly summarises recent research on the neural basis of cognition in depression. Two broad areas are covered: emotional and non-emotional processing. We consider how research findings support models of depression based on disrupted cortico-limbic circuitry, and how modern connectivity analysis techniques can be used to test such models explicitly. Finally we discuss clinical implications of cognitive imaging in depression, and specifically the possible role for these techniques in diagnosis and treatment planning.
引用
收藏
页数:9
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